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Venous Insufficiency of the Lower Extremities –⁠ A Diverse Range of Risks, Manifestations, and Complications

20. 11. 2020 Source: Venous Insufficiency

Although initially often asymptomatic, chronic venous insufficiency includes a variety of symptoms. Some of its manifestations can be irreversible, increasing the socio-economic burden that this disease, especially in its advanced stages, represents. German authors have summarized the latest findings on the epidemiology, risks, pathogenesis, manifestations, and complications of CVI in their review.

Geriatrics and Nutrition in Old Age -⁠ Invitation

We invite you to watch a webinar dedicated to the topic of nutrition in old age. The impetus for its creation was the fact that from September 1, 2020, physicians specializing in geriatrics are allowed...
19. 11. 2020 Source: Enteral Nutrition
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Effect of Zolpidem on the Quality of Overnight Sleep in Terms of Episodic Memory Formation

Zolpidem is a non-benzodiazepine hypnotic used for the short-term treatment of insomnia in adults. Previous studies have shown that this gamma-aminobutyric acid (GABA-A) agonist stimulates the…
19. 11. 2020 Source: Geriatric Patient
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Idiopathic Pulmonary Fibrosis: What Can a General Practitioner Do?

When a previously healthy patient becomes breathless, it's never good news. Among the particularly serious issues that breathlessness can signal is idiopathic pulmonary fibrosis (IPF). However, its…
19. 11. 2020 Source: Pulmonary Fibrosis
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Direct Oral Anticoagulants and Their Reversal Agents –⁠ Current Options

In the last 10 years, the options for anticoagulant therapy have expanded with the introduction of direct oral anticoagulants (DOACs). It appears that DOACs may soon replace warfarin in the first…
19. 11. 2020 Source: Anticoagulant Treatment
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Two Is Not Enough: Efficacy of Alemtuzumab in Subsequent Cycles

The goal of the recent pooled analysis of the CARE-MS and TOPAZ study results published in the journal Multiple Sclerosis was to evaluate the efficacy and safety of alemtuzumab in patients with…
18. 11. 2020 Source: Multiple Sclerosis
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Different doses of LMWH in hospitalized patients with COVID-19 –⁠ interim experience

Many experts recommend administering heparin to patients with COVID-19 as part of anticoagulant prophylaxis, especially in severe forms of this infection. However, data on dosage, administration…
18. 11. 2020 Source: Thromboprophylaxis

Depakine Chrono versus Other Valproates in the Treatment of Bipolar Disorder

Bipolar disorder is among the most severe psychiatric illnesses, and if not treated properly, it can negatively affect the patient's quality of life. Does switching therapy from other valproates to…
18. 11. 2020 Source: Bipolar Disorder
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Efficacy of Romiplostim in Children with Persistent or Chronic ITP

The effect of the thrombopoietin receptor agonist romiplostim in adult patients with immune thrombocytopenia (ITP) is well known. Equally important, however, are data on its treatment in children —…
18. 11. 2020 Source: Immune Thrombocytopenia
Výsledky

Experiences with AHA in Two Czech Centers and Risk Factor Evaluation

This summer, the journal Haemophilia published the results of an analysis of data from a relatively large Czech cohort of patients with acquired hemophilia A (AHA). The goal was to identify risk…
18. 11. 2020 Source: Hemophilia

Therapy of Chronic Leg Ulcers According to Evidence-Based Medicine

Chronic ulcers on the lower extremities are defined as trophic defects that show no signs of healing after 3 months of appropriate treatment or are not healed even after 12 months of treatment. Their...
15. 11. 2020 Source: Wound Healing
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FLEX –⁠ A New Predictive Model for Assessing Follicular Lymphoma Risks

Overall survival of patients with advanced-stage follicular lymphoma (FL) who experience early disease progression after chemotherapy remains low. Currently used clinical prognostic models do not…
14. 11. 2020 Source: Non-Hodgkin Lymphomas and CLL
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Socio-economic Benefits of Using Obinutuzumab in 1st Line Treatment of Follicular Lymphoma

Pharmacoeconomic analyses remind us that our patients' diseases affect not only themselves or the healthcare system, but also have an impact on the entire society. Patients with follicular lymphoma…
14. 11. 2020 Source: Non-Hodgkin Lymphomas and CLL

Expression of PD-L1 in Patients with Advanced Non-Small Cell Lung Cancer

An international team of authors published a systematic review addressing the relationship between the programmed cell death receptor ligand (PD-L1) and important clinical characteristics of patients…
14. 11. 2020 Source: Immunotherapy in Oncology
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Case Study with Voting: Intensification of Type 2 Diabetes Therapy in a Chronically Treated Patient. How to Proceed According to Current Recommendations?

We have prepared an interactive case study for you with a 70-year-old patient with decompensated Type 2 Diabetes. The patient was diagnosed with DM eight years ago. What treatment approach would you choose?...
12. 11. 2020 Source: Diabetes
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