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Alemtuzumab –⁠ Does Age Matter? Or Not?

18. 10. 2021 Source: Multiple Sclerosis

The authors of a study published this year focused on the safety and efficacy of alemtuzumab in patients with relapsing-remitting multiple sclerosis (RRMS). How did it perform over the observed period in patients of different age categories?

Does Teriflunomide Bloom at Every Age?

What impact does age have on the effectiveness of multiple sclerosis (MS) therapy in real-world clinical practice? How do the outcomes differ for patients treated with teriflunomide considering their…

18. 10. 2021 Source: Multiple Sclerosis

How Does Memantine Currently Stand in Alzheimer's Disease and Other Dementias

A comprehensive meta-analysis from 2019 examined the effect and safety of administering memantine, particularly in patients with moderate to severe Alzheimer's disease. How did memantine fare?

17. 10. 2021 Source: Cognitive in the treatment of Alzheimer's disease

covid lékař pacientka nemocnice koronavirus vyšetření

Treatment of Metastatic Colorectal Cancer During the COVID-19 Pandemic

In the conditions of the coronavirus pandemic, it is difficult to maintain good accessibility to ongoing comprehensive oncological care, and thus the quality of life of patients. An international…

15. 10. 2021 Source: Treatment of Gastrointestinal Carcinomas

Biosimilar MB02 as an Alternative to Bevacizumab in Lung Cancer Treatment

The STELLA clinical trial aimed to evaluate the efficacy, safety, and immunogenicity of MB02, a biosimilar to bevacizumab, in patients with advanced non-small cell lung cancer.

15. 10. 2021 Source: Oncological Treatment

Efficacy and Safety of Gefitinib in Combination with Chemotherapy vs. Chemotherapy Alone in the Treatment of Advanced NSCLC

Non-small cell lung cancer (NSCLC) remains a disease with high mortality. The meta-analysis presented below compared the efficacy and safety of gefitinib in combination with chemotherapy versus…

15. 10. 2021 Source: Oncological Treatment

Nasal Smear as a Modern and Gentle Diagnostic Method for Allergic Rhinitis

Up to 130 million Europeans suffer from allergic rhinitis. Until now, standard diagnostic methods have been skin prick tests and laboratory blood tests. Both methods, however, present significant…

14. 10. 2021 Source: Allergic Reactions

Physiological and Clinical Effect of Romiplostim in the Treatment of ITP

Romiplostim in the treatment of immune thrombocytopenia (ITP) has demonstrated safety and the promise of long-term remission, enabling many pediatric and adult patients to discontinue treatment and…

11. 10. 2021 Source: Immune Thrombocytopenia

Administration of Romiplostim in Patients with ITP in Real-World Practice in Central Europe

Data from the PLATON study on the administration of romiplostim in real-world clinical practice in Central and Eastern Europe confirmed very good efficacy in patients with newly diagnosed,…

11. 10. 2021 Source: Immune Thrombocytopenia

Vaccination Against COVID-19 in Patients Treated With Anticoagulants

Canadian professional societies and the National Health Service (NHS) in the United Kingdom recommend COVID-19 vaccination even for patients treated with anticoagulants. The benefit of vaccination in…

11. 10. 2021 Source: Anticoagulant Treatment

Importance of Testing for Iron Deficiency in Patients with Chronic Heart Failure and Treatment Options

Intravenous iron application in patients with heart failure and iron deficiency is now part of ESC guidelines aimed at improving symptoms, increasing exercise tolerance and quality of life in these…

5. 10. 2021 Source: Iron Deficiency and Anemia

Effects of Metformin on the Cardiovascular System of Patients with Diabetes, but Also Without It

Diabetes mellitus (DM) is considered an independent risk factor for the development of ischemic heart disease (IHD). The prevalence of IHD is continuously increasing, making early detection of risk…

5. 10. 2021 Source: Modern Treatment of Diabetes

Recommendations for Lipid Administration in Patients on Home Parenteral Therapy

Home parenteral therapy is an important part of treatment for patients with chronic intestinal failure who cannot achieve adequate nutrition through enteral feeding. An integral component of this…

4. 10. 2021 Source: Parenteral Nutrition

No deficiency of essential fatty acids in home parenteral nutrition

A Dutch-British study, the results of which were published in the Journal of Parenteral and Enteral Nutrition, addressed the issue of potential deficiency of essential fatty acids in patients using…

4. 10. 2021 Source: Parenteral Nutrition

Does Administration of Saline Make a Crucial Difference Compared to Balanced Crystalloids in Critically Ill Patients?

A study published in the New England Journal of Medicine provided data on mortality and deterioration of renal function in adult patients in intensive care units, depending on whether they received…

4. 10. 2021 Source: Parenteral Nutrition

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