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Efficacy and Safety of Enoxaparin as Bridging Anticoagulant Therapy After Ventricular Assist Device Implantation

1. 10. 2021 Source: Thromboprophylaxis

The implantation of a ventricular assist device has become an increasingly common method in the treatment of end-stage heart failure in recent years. The implantation of the device necessitates anticoagulant therapy. In the long term, warfarin is most often used according to guidelines, but there are no clear recommendations for early postoperative anticoagulant therapy. The aim of a clinical study published last year was to evaluate the efficacy and safety of enoxaparin as bridging anticoagulant therapy after device implantation within a…

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Administration of Low-Molecular-Weight Heparin After Hemorrhagic Stroke: What Is the Appropriate Timing?

Hemorrhagic stroke (HS) is a condition that raises doubts and concerns about anticoagulation. Is early prevention of thromboembolic complications appropriate?
30. 9. 2021 Source: Thromboprophylaxis
muž kašel rouška astma muž kašle do roušky covid

Asthma and Prognosis of Patients with COVID-19

The impact of asthma, its severity, and treatment on the prognosis of patients infected with the SARS-CoV-2 coronavirus was examined in an observational study published this spring.
23. 9. 2021 Source: Asthma under control
starší muz rozhovor u lekarky

Patient with Moderate Hemophilia A and Development of FVIII Inhibitor in Old Age and Atrial Fibrillation −⁠ Interactive Case Study

MUDr. Petr Smejkal, Ph.D., from the Department of Clinical Hematology, FN Brno, has prepared a case study for you of a patient born in 1941, diagnosed with hemophilia A at around 10 years of age. In 2013,...
22. 9. 2021 Source: Quality Life Even with Hemophilia
štítná žláza grafika

How Gut Microbiota Affects Thyroid Function

The composition of gut microbiota has a significant impact on the human body. Studies conducted so far have found a correlation between dysbiosis and a range of diseases, including thyroid disorders…
22. 9. 2021 Source: Thyroid Disorders
Štítná žláza

Relationship between Thyroid Gland Echogenicity and Its Function in Pediatric Patients with Hashimoto's Thyroiditis

Hashimoto's (chronic lymphocytic) thyroiditis is the most common cause of acquired hypothyroidism in both adults and pediatric patients in developed countries. The study presented below explored the…
22. 9. 2021 Source: Thyroid Disorders

Is the Quality of Life for Patients with Atrial Fibrillation and Heart Failure Comparable When Treated with Bisoprolol and Digoxin?

The British RATE-AF study, published in December 2020 in the JAMA journal, compared the impact on improving the quality of life in patients with permanent atrial fibrillation (AF) and symptoms of…
21. 9. 2021 Source: Cardiovascular Continuum
migrena, léčba silné migreny

Eletriptan as an effective and safe drug in acute migraine therapy

In the pharmacotherapy of acute migraine attacks, a pharmacologically diverse group of triptans is particularly used. The choice of the right antimigraine drug should be individualized, based on the…
20. 9. 2021 Source: Treatment of Severe Migraine
hemofilie_zkumavky

Individualized Prophylaxis with Achieving Higher Minimum Levels as a Possible Path to Optimal Treatment of Hemophilia A

Prophylactic administration of factor VIII (FVIII) concentrate is the standard of care for individuals with severe hemophilia A. Traditionally, the goal of prophylaxis has been to maintain minimum…
15. 9. 2021 Source: Hemophilia
Metamizol analgetika

Metamizole at a Glance and in Practice –⁠ Effective Non-Opioid Analgesic for All Ages

The regular webinar of the General Medicine Society of ČLS JEP this spring, besides addressing the current coronavirus situation, also focused on the issue and treatment of pain in its specialized…
15. 9. 2021 Source: Analgesia

Biosimilar Bevacizumab in Patients with Non-Small Cell Lung Cancer

Biosimilar drugs are essentially analogous to generics for biological medicines. The patent protection for the original bevacizumab product will expire in the European Union in 2022. Consequently,…
15. 9. 2021 Source: Oncological Treatment

Position of Generic Drugs in Oncology: What Are Their Main Advantages?

Generics –⁠ as is well known –⁠ are products containing the same active substance as the original medicinal product, which can enter the market after the patent protection of the original drug has…
15. 9. 2021 Source: Oncological Treatment
pohotovost

Monocyte Distribution Width as a New Indicator of Sepsis in High-Risk Patients

Most septic patients are first encountered in the emergency department, where sepsis detection is often delayed, partly due to a lack of effective biomarkers. The study presented below evaluated the…
13. 9. 2021 Source: Because
sepse

New Hematological Biomarker for Early Diagnosis of Sepsis

Sepsis is one of the leading causes of mortality and healthcare expenditure worldwide. Early diagnosis and treatment of septic conditions improve patient prognosis. However, the initial symptoms of…
13. 9. 2021 Source: Because
Kašel

Interstitial Lung Processes and Their Fibrotic Progression

Interstitial lung processes (ILPs) include more than 200 clinical units that share diffuse involvement of lung tissue and thus have similar clinical, radiological, and functional findings. However,…
10. 9. 2021 Source: Progressive Interstitial Pulmonary Processes
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