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Quick Relief from Severe AD Symptoms –⁠ Dupilumab for Children Aged 6 Years and Older

1. 11. 2021 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation

Children aged 6-12 with severe atopic dermatitis (AD) have very limited treatment options. The studies presented below demonstrate how effective and safe dupilumab, a monoclonal antibody targeting interleukins 4 and 13, is in their case. Since October, this medication is newly covered even for children from 6 years of age.

mikrobiom

Probiotic L. reuteri in combination with vitamin D3 and krill oil suppresses experimental intestinal inflammation

Previous placebo-controlled studies have shown that oral administration of a probiotic containing Lactobacillus reuteri is associated with a significant increase in plasma levels of 25-hydroxyvitamin...
29. 10. 2021 Source: GI, colic and microbiome
roztoč

Dust Mite Allergy and the Risk of Sleep-Disordered Breathing

New York authors in their recently published retrospective analysis tested the hypothesis that individuals with allergic rhinitis caused by dust mite allergy have an increased risk of breathing disorders...
29. 10. 2021 Source: Dust Mite Allergy
sestra srdce

Effect of Empagliflozin on Clinical Stability in Patients with Heart Failure and Reduced LV Ejection Fraction

Previous studies have shown that the oral antidiabetic drug empagliflozin reduces the risk of death from cardiovascular causes or hospitalization for heart failure in patients with heart failure with…
29. 10. 2021 Source: Diabetes
Echokardiografie_srdce_monitoring_kardiomyopatie_angina_pectoris_septum_venózní_hypertenze

Overlap of SGLT2 Inhibitors from Diabetology to Cardiology

As recent research shows, one of the modern groups of antidiabetic drugs -⁠ SGLT2 inhibitors, also known as gliflozins -⁠ brings benefits not only in diabetology but also in cardiology and nephrology.…
29. 10. 2021 Source: Diabetes
srdce srdeční selhání

Heart Failure in the Light of New ESC Guidelines

Dear Doctor, The Czech Society of Internal Medicine of ČLS JEP invites you to watch the symposium, which will take place on Wednesday, November 3rd, at 5 PM.
You can find more information in the…
27. 10. 2021 Source: Heart Failure
srdce srdeční selhání

Heart Failure in Light of New ESC Guidelines

Dear Doctor, The Czech Society of Internal Medicine ČLS JEP invites you to watch the symposium, which will take place on Wednesday, November 3rd at 5 PM.
You can find more information in the attached…
27. 10. 2021 Source: Anticoagulant Treatment
Muž_obrázek hlavy_dav lidí_schizofrenie

Early Intervention in the Early Phase of Psychosis

A meta-analysis of 10 randomized studies examined whether early intervention in the initial phase of psychosis in patients with schizophrenia is associated with better outcomes than usual care.
27. 10. 2021 Source: Modern Treatment of Schizophrenia
kardio tepna

Association between Cardiovascular Risk Factors and Cognitive Disorders in Patients with Schizophrenia

Schizophrenia is a disease characterized by a certain degree of cognitive impairment, but also an increased risk of cardiovascular diseases, which are often the cause of deteriorating cognitive…
27. 10. 2021 Source: Modern Treatment of Schizophrenia
žena postel polštář peřina spánek únava deprese

How Do Sleep and Depression Influence Each Other?

It is known that most patients with depression encounter some form of sleep disorder. In the following text, we briefly explore the complex relationship between depression and sleep and offer some…
27. 10. 2021 Source: Depression and Anxiety
Dítě_kašel_postel

Conditions for the Use of Mucolytics in Children Are Tightening in Europe −⁠ Which Treatment Is Preferred?

There has been a long-standing discussion among experts regarding the benefits of individual mucomodulatory drugs in the treatment of productive cough in children. According to current…
25. 10. 2021 Source: Cough Therapy
krvácení, nos, krev, bolest

Optimization of Romiplostim Administration in ITP Treatment

In their newly published review article, authors from several American institutions summarize findings on the role of romiplostim in the treatment of immune thrombocytopenia (ITP) and its efficacy…
22. 10. 2021 Source: Immune Thrombocytopenia
žena, únava, bolest

Fatigue as a Significant Symptom of Immune Thrombocytopenia from the Patients' Perspective

The I-WISh survey assessed the impact of immune thrombocytopenia (ITP) and its treatment on patients' lives. Patients identified fatigue as the most frequent, severe, and persistent symptom…
22. 10. 2021 Source: Immune Thrombocytopenia
hemofilie skumavka

Final Analysis of the STASEY Study: How Did Emicizumab Fare in the Prophylaxis of Hemophilia A Patients with FVIII Inhibitors?

The July virtual congress of the International Society on Thrombosis and Haemostasis (ISTH) 2021 offered a variety of interesting topics. Among the poster presentations, data from the multicenter, single-arm,...
21. 10. 2021 Source: Rare Diseases in Hematology
COVID 19 LEŽÍCÍ

Mucormycosis Associated with COVID-19 –⁠ Case Report and Review of Current Knowledge

Systemic corticosteroids are among the treatments used for patients with severe COVID-19. These patients are at increased risk of opportunistic bacterial and fungal infections. Pulmonary aspergillosis...
20. 10. 2021 Source: Anti-Infectives
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