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Evaluation of Continuity of Care in Patients with mCRC –⁠ Baseline Characteristics of Participants in the PROMETCO Study

9. 9. 2021 Source: Treatment of Gastrointestinal Carcinomas

During this year's World Congress of the European Society for Medical Oncology (ESMO) on gastrointestinal malignancies, the baseline characteristics of participants in the ongoing PROMETCO study, which focuses on evaluating the continuity of care in patients with metastatic colorectal cancer (mCRC), were presented.

kongres doktorov

Trifluridine/tipiracil in Real Clinical Practice –⁠ Current Data from Spain

Trifluridine/tipiracil is indicated for the treatment of patients with refractory metastatic colorectal cancer (mCRC), where clinical studies have shown it extends overall survival (OS) and progression-free...
9. 9. 2021 Source: Treatment of Gastrointestinal Carcinomas
CLL prezentace Abbvie ilustrační

Evaluation of Treatment Response in CLL

The size of lymph nodes, liver, spleen, blood cell counts, systemic symptoms... Changes in these indicators provide clear information on whether the disease of chronic lymphocytic leukemia (CLL) has progressed,...
9. 9. 2021 Source: Chronic Lymphocytic Leukemia
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Idiopathic Pulmonary Fibrosis: Can This Disease Be Named More Precisely?

Much about idiopathic pulmonary fibrosis (IPF) is still unknown. Some experts would like to reclassify this disease. What classification options are available? What would a focus on the "progressive…
9. 9. 2021 Source: Progressive Interstitial Pulmonary Processes
statistiky business grafy kancelář práce studie

Brigatinib in the Therapy of ALK-Positive NSCLC in Patients Refractory to Crizotinib Therapy –⁠ Results of the Final Analysis of Clinical Studies

Previously published results of clinical studies have shown that in patients refractory to crizotinib therapy, the administration of brigatinib led to a high rate of therapeutic response (systemic…
9. 9. 2021 Source: Non-Small Cell Lung Cancer
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Brigatinib in the Therapy of ALK-Positive NSCLC –⁠ First Results of the J-ALTA Study

Brigatinib is an anaplastic lymphoma kinase (ALK) inhibitor with broad and potent activity against ALK gene mutations causing resistance to ALK inhibitor therapy (ALKi). In patients refractory to…
9. 9. 2021 Source: Non-Small Cell Lung Cancer
srdce cevy cholesterol krev ateroskleroza

Ivabradine and/or Sacubitril/Valsartan in the Treatment of Heart Failure with Reduced Ejection Fraction

Ivabradine and sacubitril/valsartan are used in the second line of therapy for heart failure with reduced ejection fraction (HFrEF). The aim of the study presented below was to evaluate the…
7. 9. 2021 Source: Chronic Heart Failure and Lipidology
rano dělá den žena úsměv pohoda nálada

Variability of COPD Symptoms During the Day and Impact on Patients' Morning Routine –⁠ Survey Results

Chronic obstructive pulmonary disease (COPD) is viewed, unlike bronchial asthma, as a condition with a more chronic course and less variability of symptoms throughout the day. The study presented…
7. 9. 2021 Source: COPD
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Atectura® and Enerzair® from May 1, 2021 with Health Insurance Coverage

The fixed combination of indacaterol acetate (LABA) and mometasone furoate (ICS) Atectura® and the fixed triple combination, which in addition to these two substances also includes glycopyrronium…
2. 9. 2021 Source: Asthma under control
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New Strategies in the Treatment of Schizophrenia

Schizophrenia was primarily associated with dopamine dysfunction. Previous and current treatments have mainly targeted the mesolimbic dopamine pathway in the CNS and D2 receptors. However, the cited…
30. 8. 2021 Source: Schizophrenia and Antipsychotics
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Is it safe to start dabigatran in the first days after ischemic stroke?

For patients after cardioembolic ischemic stroke (iCMP), starting anticoagulant therapy is crucial, but it is not strictly defined how many days after iCMP it is ideal to begin. The article provides…
27. 8. 2021 Source: Anticoagulant Treatment
chopn plice studie inhalator astma data

Is the combination of tiotropium/olodaterol proven more effective in reducing the risk of clinically significant worsening of COPD compared to monotherapy?

Given the heterogeneity of chronic obstructive pulmonary disease (COPD), the use of a composite parameter that includes lung function, the occurrence of exacerbations, and quality of life offers a…
26. 8. 2021 Source: COPD
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Impact of Chronic Urticaria on Patients' Quality of Life and Society

An international team of dermatologists has mapped out the impact of chronic urticaria on various aspects of patients' lives and the economic burden this long-term disease, without available causal…
25. 8. 2021 Source: Allergic Reactions
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Perioperative substitution therapy in patients with vWD must be tailored

Even in cases of von Willebrand disease (vWD), available data supports the need for individualized approaches in ensuring surgical procedures to prevent FVIII accumulation and high factor consumption.
25. 8. 2021 Source: Von Willebrand Disease
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Another Piece of the Puzzle for More Accurate Dosing of Clotting Factors in von Willebrand Disease

A study published last year in the Journal of Thrombosis and Haemostasis presents the results of Dutch hematologists who created a pharmacokinetic model to refine the dosing of clotting factors…
25. 8. 2021 Source: Von Willebrand Disease
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