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Treatment with Dupilumab in Severe Corticosteroid-Dependent Bronchial Asthma – A Case Study
We present the case of a 36-year-old woman with severe corticosteroid-dependent asthma with numerous comorbidities and complications due to long-term systemic corticosteroid therapy. Significant improvements in quality of life, asthma control, regression of skin changes in atopic dermatitis, and reduction in methylprednisolone consumption for this patient were only achieved after the initiation of biological treatment. Dupilumab, a monoclonal antibody against the α subunit of the receptor for interleukins IL-4 and IL-13, which is approved for…

Comparison of Enoxaparin and Unfractionated Heparin in Hospitalized Patients in Terms of Clinical and Cost Effectiveness
Thromboembolic disease represents one of the severe complications in hospitalized patients. Low…

Efficacy of L. reuteri DSM 17938 in the Treatment of Infantile Colic
Infantile colic represents a syndrome of behavioral disorders in infants characterized by episodes…

Continuation of Treatment with Tofacitinib in Rheumatoid Arthritis – Real-World Clinical Practice Data
The oral Janus kinase inhibitor tofacitinib has been extensively tested in patients with rheumatoid…

COVID-19 in Patients with Acquired Hemophilia A − Case Reports
At the XXVIII. Pařízek Days held in Ostrava, on the afternoon of March 17, 2022, Dr. Anna Maria…

Is it beneficial to combine etanercept and methotrexate in the treatment of psoriatic arthritis?
The study presented below by Canadian, American, and British authors focused on comparing the…

Participation in sports activities, frequency and severity of sports injuries in children with hemophilia
Children with hemophilia used to be discouraged from engaging in sports activities due to the…

Acquired Hemophilia A Newly Diagnosed in an Elderly Patient − A Case Report
At the XXVIIIth Pařízek Days held in Ostrava, a case of acquired hemophilia A, recently addressed…

PHD 2022: In the treatment of multiple myeloma we have achieved significant progress, confirm real-world data
The treatment options for multiple myeloma (MM) have significantly advanced over the past 10 years,…

Hodgkin Lymphoma in a Summary of News from Post-ASH 2021
Dr. Anna Suredová from the Clinical Hematology Department of the Catalonian Oncology Institute in…