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Effectiveness of the Venetoclax/Rituximab Combination in the Treatment of CLL –⁠ 5-Year Follow-Up Data

12. 4. 2021 Source: Chronic Lymphocytic Leukemia

At the virtual 62nd Annual Meeting of the American Society of Hematology (ASH), updated results of a clinical evaluation of the treatment of patients with refractory/relapsed chronic lymphocytic leukemia (R/R CLL) using venetoclax in combination with rituximab were presented.

Retention –⁠ An Overlooked Parameter of Incontinence Products

In the Czech Republic and other European countries, the main criterion when choosing an incontinence product, apart from its size, is primarily absorption. This defines the amount of fluid the…

9. 4. 2021 Source: Incontinence

Hemorrhoidal Disease –⁠ A Civilization Illness Responsible for Perianal Discomfort

According to estimates, almost every second Czech will experience at least one attack of hemorrhoidal disease. Symptomatic hemorrhoids are found in about 5% of the population. Prevalence depends to…

8. 4. 2021 Source: Venous Insufficiency

Chemotherapy as a Risk Factor for Severe COVID-19 Course?

During the coronavirus pandemic, patients with malignant neoplastic diseases are considered an at-risk group. Whether chemotherapy is a risk factor for a more severe course of COVID-19 was the…

8. 4. 2021 Source: Antiemetic Therapy

Impact of Antiemetic Prophylaxis on Quality of Life of Patients Treated with Chemotherapy –⁠ Data from Practice

Chemotherapy-induced nausea and vomiting (CINV) is a relatively common complication of cancer treatment with a significantly negative impact on patients' quality of life. A large prospective analysis…

8. 4. 2021 Source: Antiemetic Therapy

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Adjuvant Treatment of Early Invasive HER2+ Breast Cancer −⁠ Results of the Katherine Study

Women with breast cancer found to have residual invasive disease during surgery after neoadjuvant chemotherapy and HER2-targeted therapy have a significantly worse prognosis. For these patients, the…

8. 4. 2021 Source: Breast Carcinoma

zdravý životní styl sport jídlo pohyb cvičení medicína

Sport as an Important Part of the Life of Hemophiliacs

People with congenital bleeding disorders have very diverse approaches to sports and exercise. The possibility of preventing bleeding by administering safe and effective medications for these…

7. 4. 2021 Source: Hemophilia with Movement

Turoctocog Alfa Pegol in Surgical Procedures –⁠ Experiences from Pathfinder 3 and 5 Studies

The Haemophilia journal published data in May 2020 from 2 studies that summarize experiences with turoctocog alfa pegol during surgical procedures in adults, adolescents, and children with hemophilia…

7. 4. 2021 Source: Hemophilia with Movement

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Does Beta-Blocker Therapy Reduce the Cardiovascular Benefit of Aerobic Exercise in Patients with Arterial Hypertension?

Regular aerobic exercise is generally recommended for patients suffering from arterial hypertension to reduce blood pressure values, improve physical fitness, and other parameters. The intensity of…

5. 4. 2021 Source: Cardiovascular Continuum

Change in Release of Medication Pradaxa

Dear Doctor,
We would like to inform you that from April 1, 2021, based on the decision of the State Institute for Drug Control (SÚKL), the release of the medication (LP) Pradaxa (dabigatran-etexilat…

31. 3. 2021 Source: Anticoagulant Treatment

How does Benzalkonium Chloride and Prostaglandins Affect Meibomian Gland Epithelial Cells?

Benzalkonium chloride is commonly used in eye drops intended for glaucoma treatment due to its preservative effect. However, in recent years, it has been shown to cause damage to both superficial and…

31. 3. 2021 Source: Treatment of Glaucoma

Effect of Prostaglandin Analogues With and Without Preservatives on Meibomian Glands in Glaucoma Patients

Prostaglandin analogues (PGA) have become a standard in the treatment of open-angle glaucoma. However, their long-term use may be associated with eye irritation or damage to the Meibomian glands. The…

31. 3. 2021 Source: Treatment of Glaucoma

Post-COVID Depression: How Can a General Practitioner Help?

Psychiatrists confirm that mental health plays an increasingly important role in the context of the COVID-19 pandemic. Although exact data will only be available over time, as the impacts in this…

30. 3. 2021 Source: Depression and Anxiety

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If Suicides Were COVID-19... or Why We Still Overlook a Significant Cause of Premature Deaths?

More than a year since the start of the pandemic, the SARS-CoV-2 coronavirus has claimed 2.8 million lives globally, with 127 million recorded cases of COVID-19 (as of March 29, 2021). According to…

30. 3. 2021 Source: Depression and Anxiety

Léky proti rakovinné buňce jako zdravotní péče lékařský koncept pro farmaceutický lék

Lorlatinib showed significant benefit in 1st line treatment of advanced ALK-positive non-small cell lung carcinoma

In the international CROWN study, lorlatinib compared to crizotinib led to a 72% reduction in the risk of disease progression or death and significant improvement in intracranial response to…

30. 3. 2021 Source: Genetic Profile and Treatment of NSCLC

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