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Does dabigatran use in women with acute venous thromboembolism reduce the risk of uterine bleeding compared to warfarin?

14. 4. 2021 Source: Anticoagulant Treatment

The use of new oral anticoagulants (NOACs) in patients with deep vein thrombosis is associated with a more favorable safety profile compared to warfarin. However, direct factor Xa inhibitors (rivaroxaban, apixaban, edoxaban) pose a higher risk of abnormal uterine bleeding. The study presented below compared the risk of this bleeding when using dabigatran (a direct thrombin inhibitor) and warfarin.

Effect of Short-Term and Long-Term Stress on Heart Rate Variability

Acute and chronic stress significantly affects the cardiovascular (CV) system. The study presented below examines the effects of both acute and chronic stress on heart rate variability in 50 healthy…

13. 4. 2021 Source: Cardiovascular Continuum

Experiences with Long-term Treatment of Psoriasis with Interleukin 17A Inhibitor

The current publication of the long-term extension of the UNCOVER-3 study, which focused on the treatment of psoriasis with ixekizumab, describes the efficacy and safety of 4 years of use of this…

13. 4. 2021 Source: Biological Treatment

Options for Preventing Enteral Nutrition Intolerance in Mechanically Ventilated Patients in the ICU

Standards of care for critically ill patients recommend enteral nutrition for those on mechanical ventilation. A recently published study addressed the question of how to identify patients at risk of…

12. 4. 2021 Source: Enteral Nutrition

European Registry of Patients with Alpha-1 Antitrypsin Deficiency EARCO Enrolls Patients

Insufficient identification of patients with alpha-1 antitrypsin deficiency (AATD) and a lack of knowledge about this disease have led to the launch of the European Registry EARCO, which is currently…

12. 4. 2021 Source: Deficiency of Alpha-1-Antitrypsin

Can alpha-1-antitrypsin deficiency affect severity and higher mortality in COVID-19 patients?

Alpha-1-antitrypsin (AAT) deficiency is commonly found in the European population. The most cases are recorded in countries with the highest COVID-19 mortality rates. Are there direct correlations?

12. 4. 2021 Source: Deficiency of Alpha-1-Antitrypsin

Effectiveness of the Venetoclax/Rituximab Combination in the Treatment of CLL –⁠ 5-Year Follow-Up Data

At the virtual 62nd Annual Meeting of the American Society of Hematology (ASH), updated results of a clinical evaluation of the treatment of patients with refractory/relapsed chronic lymphocytic…

12. 4. 2021 Source: Chronic Lymphocytic Leukemia

Retention –⁠ An Overlooked Parameter of Incontinence Products

In the Czech Republic and other European countries, the main criterion when choosing an incontinence product, apart from its size, is primarily absorption. This defines the amount of fluid the…

9. 4. 2021 Source: Incontinence

Hemorrhoidal Disease –⁠ A Civilization Illness Responsible for Perianal Discomfort

According to estimates, almost every second Czech will experience at least one attack of hemorrhoidal disease. Symptomatic hemorrhoids are found in about 5% of the population. Prevalence depends to…

8. 4. 2021 Source: Venous Insufficiency

Chemotherapy as a Risk Factor for Severe COVID-19 Course?

During the coronavirus pandemic, patients with malignant neoplastic diseases are considered an at-risk group. Whether chemotherapy is a risk factor for a more severe course of COVID-19 was the…

8. 4. 2021 Source: Antiemetic Therapy

Impact of Antiemetic Prophylaxis on Quality of Life of Patients Treated with Chemotherapy –⁠ Data from Practice

Chemotherapy-induced nausea and vomiting (CINV) is a relatively common complication of cancer treatment with a significantly negative impact on patients' quality of life. A large prospective analysis…

8. 4. 2021 Source: Antiemetic Therapy

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Adjuvant Treatment of Early Invasive HER2+ Breast Cancer −⁠ Results of the Katherine Study

Women with breast cancer found to have residual invasive disease during surgery after neoadjuvant chemotherapy and HER2-targeted therapy have a significantly worse prognosis. For these patients, the…

8. 4. 2021 Source: Breast Carcinoma

zdravý životní styl sport jídlo pohyb cvičení medicína

Sport as an Important Part of the Life of Hemophiliacs

People with congenital bleeding disorders have very diverse approaches to sports and exercise. The possibility of preventing bleeding by administering safe and effective medications for these…

7. 4. 2021 Source: Hemophilia with Movement

Turoctocog Alfa Pegol in Surgical Procedures –⁠ Experiences from Pathfinder 3 and 5 Studies

The Haemophilia journal published data in May 2020 from 2 studies that summarize experiences with turoctocog alfa pegol during surgical procedures in adults, adolescents, and children with hemophilia…

7. 4. 2021 Source: Hemophilia with Movement

cvičení pohyb venku muž cvičící sport protahování senior

Does Beta-Blocker Therapy Reduce the Cardiovascular Benefit of Aerobic Exercise in Patients with Arterial Hypertension?

Regular aerobic exercise is generally recommended for patients suffering from arterial hypertension to reduce blood pressure values, improve physical fitness, and other parameters. The intensity of…

5. 4. 2021 Source: Cardiovascular Continuum

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