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Telmisartan – antihypertensive with cardioprotective effects
Sartans are potent inhibitors of the AT1 receptor for angiotensin II widely used in the therapy of arterial hypertension. Given that chronic activation of the renin-angiotensin-aldosterone system (RAAS) plays an important role not only in the pathogenesis of arterial hypertension but also in the pathogenesis of atherosclerosis and the development of other cardiovascular diseases, the question arises whether the administration of sartans is associated with a broader cardioprotective effect. Telmisartan is the first representative of this group…

Does the choice of therapy for primary hypertension in patients with COVID-19 affect the severity of the disease?
The effect of two commonly used antihypertensives was evaluated in a randomized clinical trial in…

Prim. Pavel Jindra: Biosimilars are an accessible and effective treatment modality in hematooncology
“Based on our experience so far, biosimilars represent an effective and safe alternative to…

Combined Hormonal Contraception in the Treatment of Dysmenorrhea
Dysmenorrhea troubles many women of reproductive age and can deteriorate their quality of life,…

Parenteral Nutrition in Oncological Patients in Current ESPEN Recommendations
The current guidelines of the European Society for Clinical Nutrition and Metabolism (ESPEN)…

Parenteral Nutrition as Part of Cancer Patient Treatment
Malnutrition represents a potentially serious complication for cancer patients. If it is not…

Why can probiotics and vitamin D significantly affect human health?
Vitamin D deficiency is the most common hypovitaminosis in developed countries. It is largely…

Results of Knee and Hip Joint Arthroplasty in Hemophiliacs
Total endoprosthesis implantation represents an effective solution for the terminal stages of joint…

What Shape and Size of Tablets Do Our Patients Prefer?
The size and shape of tablets can affect patients' compliance with treatment. The following article…