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guidelines

Current Recommendations of the Expert Panel on the Management of von Willebrand Disease

4. 1. 2022 Source: Von Willebrand Disease

Von Willebrand disease (vWD) is a common congenital bleeding disorder. The care of patients with vWD involves significant variability due to bleeding manifestations and treatment options. The new recommendations from 2021 regarding the care of people with vWD are evidence-based and supported by the American Society of Hematology (ASH), the International Society on Thrombosis and Haemostasis (ISTH), the National Hemophilia Foundation USA (NHF), and the World Federation of Hemophilia (WFH). We bring you a concise summary of the key points.

Starší doktor u počítače vysvětluje mladé pacientce její zdravotní stav.

How and with What the National Registry of Primary Immunodeficiencies Benefits Specialists and Patients

Primary immunodeficiencies constitute a very heterogeneous group of congenital diseases. They affect both specific and nonspecific immunity and are classified accordingly. The care for patients with…
3. 1. 2022 Source: Hereditary Angioedema
rakovina buňky

Update of the Blue Book: What's New in the Treatment of Metastatic NSCLC with an ALK Gene Mutation?

As of March 1, 2022, the 28th update of the Blue Book by the Czech Society for Oncology of ČLS JEP was released. Let's take a look at what changes it has brought compared to the previous version in…
27. 12. 2021 Source: Genetic Profile and Treatment of NSCLC
Brain metastases

Brain Metastases Are Not an Absolute Contraindication for Antiplatelet Therapy

On one hand, there's a higher risk of thromboembolic events, and on the other, a higher risk of intracranial bleeding. Prophylactic and therapeutic interventions for blood clotting are necessary for…
27. 12. 2021 Source: Genetic Profile and Treatment of NSCLC
cancer plíce

Complete remission of ALK-positive lung cancer in a patient after multiple lines of targeted therapy –⁠ a case study

Targeted treatment for driving oncogenic mutations has significantly improved outcomes for patients with ALK-positive non-small cell lung cancer (NSCLC) as well. A case study was recently published…
27. 12. 2021 Source: Genetic Profile and Treatment of NSCLC
covid očkování medicína doktor

How Do Vaccinated MS Patients Fare with COVID-19 Antibodies?

Which disease-modifying drugs for the treatment of multiple sclerosis (MS) reduce the humoral response to COVID-19 vaccination? And does the quantity of post-vaccination antibodies vary depending on…
21. 12. 2021 Source: Multiple Sclerosis
výzkum lékař medicína laboratoř

When Teriflunomide and Interferon Join Forces

Progressive multifocal leukoencephalopathy is a nightmare for all doctors prescribing disease-modifying therapies for multiple sclerosis. How Swiss colleagues dealt with this situation is illuminated…
21. 12. 2021 Source: Multiple Sclerosis
molekuly

Fixed Combination of Tiotropium/Olodaterol in SMI Inhaler and Its Benefits in COPD Treatment

The TRONARTO study, whose conclusions were published in the International Journal of Chronic Obstructive Pulmonary Disease, addressed the issue of inhalation therapy in patients with chronic…
20. 12. 2021 Source: COPD
mladá žena u gynekologa

Protection of Ovarian Function During Breast Cancer Treatment

Women diagnosed with breast cancer of childbearing age are concerned about how to maintain ovarian function even after undergoing chemotherapy. Therefore, a team of doctors from the United Kingdom…
20. 12. 2021 Source: Oncological Treatment
guidelines doporučení

New Antidiabetic Drugs in Cardiovascular Prevention in International Recommendations

Results from studies on new antidiabetic drugs showing cardiovascular (CV) benefits of sodium-glucose cotransporter 2 inhibitors (SGLT2i, gliflozins) and glucagon-like peptide 1 receptor agonists…
20. 12. 2021 Source: Diabetes
Leukémie_lékař

Bite-Sized Pieces from EHA 2021: Two New Findings on T-Cell Lymphoma

Can a molecule that is crucial for the sensitivity of adult T-cell lymphoma or leukemia (ATLL) to NK cell cytotoxicity be identified? And what conclusions were drawn from the testing of an antibody…
15. 12. 2021 Source: Hematologic Malignancies
Schizofrenie_žena

Modern View on Schizophrenia Therapy Through the Lens of Lurasidone

At the psychiatric symposium titled 'Chance for a Better Quality of Life with a Schizophrenia Diagnosis', which took place on October 18, 2021, in Prague, Professor of Psychiatry and Molecular…
14. 12. 2021 Source: Modern Treatment of Schizophrenia
Schizofrenie_muž

Treatment of Schizophrenia in Light of New Findings

"Mental disorders constitute a significant burden on society," began Assoc. Prof. MUDr. Martin Anders, Ph.D., head of the Psychiatric Clinic at the First Faculty of Medicine, Charles University and…
14. 12. 2021 Source: Modern Treatment of Schizophrenia
NOVOROZENEC LEKAR

Cardiovascular System Affection in Children with Noonan Syndrome

Noonan syndrome is a genetically conditioned disease classified among the so-called RASopathies, caused by a germline mutation in the genes of the RAS/MAPK signaling pathway. Among other things,…
13. 12. 2021 Source: Growth Disorders
paranoidní schizofrenie_žena

Psychotic patient with high cardiometabolic risk –⁠ interactive case report

The following case report describes the treatment of a patient diagnosed with paranoid schizophrenia following a relapse of the disease. During therapy, complications arose in the form of weight…
9. 12. 2021 Source: Modern Treatment of Schizophrenia
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