News
Risk of Venous Thromboembolism and CV Events during Targeted Treatment of Nonspecific Bowel Inflammations
Authors of a freshly published study based on real-world data from the USA investigated whether there are differences in the risk of venous thromboembolism (VTE) and major cardiovascular (CV) events in patients with nonspecific bowel inflammations (IBD) who were newly prescribed the Janus kinase inhibitor (JAK) tofacitinib or the tumor necrosis factor-alpha (TNF-α) inhibitor.
Comparison of the Efficacy of Tofacitinib and Vedolizumab in the Treatment of Ulcerative Colitis After Anti-TNF Therapy Failure
Therapeutic options for ulcerative colitis resistant to anti-TNF-α antibody treatment are…
Bone density in hemophiliacs − known and less-known risk factors
Osteopenia or osteoporosis are known comorbidities of hemophilia and concern many of these…
Turoctocog Alfa in Tertiary Prophylaxis of Hemophilia A or Is It Always About Bleeding? Case Studies
This case report from our own practice concerns our experience with the treatment of hemophilia A…
Nearly 20 Years with Bevacizumab Has Brought Hope for Patients and Deeper Understanding of Solid Tumors
Bevacizumab is among the first targeted therapies used in oncology. For many indications where…
Lurasidone in Antipsychotic Therapy – A Case Study of a Virtual Patient from the Laurie Project
MUDr. Elis Bartečků, Ph.D., from the Department of Psychiatry at MU LF and FN Brno presented the…
Complex Impacts of Obesity on the Brains of People with Psychiatric Disorders
Obesity in individuals with bipolar disorder or schizophrenia is closely linked not only to higher…
Time is Blood! Impact of Diagnostic Delays on Prognosis of Patients with Acquired Hemophilia A
The famous slogan of neurologists in connection with strokes – 'Time is brain!' – can be modified…
Treatment of Depression with Persistent Severe Insomnia − Interactive Case Study
A 39-year-old patient comes to the psychiatric office due to depressive symptoms with anxiety and…
Urgent Administration of Romiplostim in Life-Threatening Bleeding Associated with ITP
Recommendations for the care of acute, especially major bleeding in individuals with severe immune…