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Efficacy and Safety of the Combination of Telmisartan and Amlodipine with Hydrochlorothiazide in the Treatment of Hypertension

8. 2. 2022 Source: Sartans in the Treatment of Hypertension

The aim of the study by Korean authors was to evaluate the efficacy and tolerability of the triple combination of telmisartan/amlodipine + hydrochlorothiazide (TAH) compared to the combination of telmisartan/amlodipine (TA) alone in patients with essential hypertension who did not respond sufficiently to a 4-week treatment with TA.

nemocniční postel rozhovor lékaře s pacientem

Effect of Administering Ferric Carboxymaltose on Quality of Life in Heart Failure Patients

The quality of life in patients with heart failure is significantly reduced. The concurrent occurrence of iron deficiency further exacerbates this situation. The AFFIRM-AHF study evaluated the impact…
7. 2. 2022 Source: Iron Deficiency and Anemia
mlady muz u zubare

CASE STUDY: Surgical Procedure in an Adolescent Patient with Severe Hemophilia A on Emicizumab Prophylaxis

This case study is narrated by MUDr. Bohumír Blažek from the Clinic of Pediatric Medicine at LF OU and FN Ostrava. The patient is a 17-year-old boy with severe hemophilia A. Several months prior to the...
1. 2. 2022 Source: Quality Life Even with Hemophilia
farmakokinetický protokol krev zkumavky

Practical Two-Point Pharmacokinetic Protocol in Hemophilia A

A recently published study confirmed the practicality of a shortened and simple pharmacokinetic protocol for patients with hemophilia A.
31. 1. 2022 Source: Hemophilia
srdce strava jídlo životní styl diabetes kardiovaskulární

Diabetic Cardiovascular Autonomic Neuropathy: How to Detect This Serious Diagnosis and Why Is It Dangerous?

Diabetic autonomic neuropathy can affect various organ systems. Cardiovascular autonomic neuropathy is one of its most severe forms with a significant impact on patient morbidity and mortality. How…
27. 1. 2022 Source: Diabetes
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Memantine in Dementia Therapy –⁠ Current Findings and Possible Future Applications

Memantine is an inhibitor of NMDA receptors, which are pathologically activated by excessive concentrations of glutamate in the synaptic cleft in Alzheimer's disease. It is indicated in the treatment…
26. 1. 2022 Source: Cognitive in the treatment of Alzheimer's disease
kůže atopic dítě dermatitida ekzém

Dupilumab Now Covered for Atopic Dermatitis in Children Older Than 6 Years

Dupilumab is now fully covered by public health insurance for pediatric patients from 6 years old with atopic dermatitis. This opens up a new possibility for pediatric patients with this condition to…
22. 1. 2022 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation
prach kychnuti

Recurring allergy symptoms after waking up? It could be due to dust mites

Allergens that are part of the feces and exoskeleton of dust mites, invisible members of human households, can cause milder symptoms like mucosal swelling, itching of the nose or throat, but also a stronger...
19. 1. 2022 Source: Dust Mite Allergy
srdce srdeční selhání

Reverse Remodeling of LV in Patients with Diabetes/Prediabetes and Heart Failure with Reduced Ejection Fraction Treated with Empagliflozin

Authors of the British study SUGAR-DM-HF published in February 2021 examined whether empagliflozin reduces left ventricle (LV) volume in patients with type 2 diabetes mellitus (DM), prediabetes, and…
14. 1. 2022 Source: Heart Failure
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Current Status in the Issue of Alpha-1-Antitrypsin Deficiency

Material by Italian and Swiss authors published in the European Respiratory Review details current insights into alpha-1-antitrypsin (AAT) deficiency and the possibilities for its diagnosis and…
12. 1. 2022 Source: Deficiency of Alpha-1-Antitrypsin
Schizofrenie_covid_rouška_žena

Mental Health During the Pandemic −⁠ and How to Alleviate Its Impacts

At the symposium during the XV Spring Interactive Conference of the General Medical Society of ČLS JEP, which was eventually held in September 2021 in Prague, Prof. MUDr. Cyril Höschl, DrSc.,…
10. 1. 2022 Source: Depression and Anxiety
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Stabilization of Liver Metastases of CRC with Trifluridine/Tipiracil in 3rd Line Therapy –⁠ Case Study

We present a case study of a man born in 1944 who underwent resection of the rectosigmoid for multiple adenocarcinomas in February 2016. Subsequently discovered liver metastases were managed with…
10. 1. 2022 Source: Treatment of Gastrointestinal Carcinomas
Kašel_muž_kapesník

Levodropropizine –⁠ a non-codeine antitussive with minimal side effects, contraindications, and drug interactions

For symptomatic treatment of dry, irritating, and exhausting cough, both codeine and non-codeine antitussives can be used. One of the non-codeine antitussives is levodropropizine. Its antitussive…
10. 1. 2022 Source: Cough Therapy

From Hell to the Light at the End of the Tunnel –⁠ A Task for Eletriptan

In recent months, under the spotlight of new biological treatments, the focus has been predominantly on the prophylactic treatment of migraines. However, we should not forget about acute therapy. In…
4. 1. 2022 Source: Treatment of Severe Migraine
T-buněčný lymfom

Brentuximab Vedotin as Another Therapeutic Option in Cutaneous T-Cell Lymphoma

Current systemic treatment for patients with cutaneous T-cell lymphoma (CTCL) unfortunately has limited efficacy, achieving low response rates and short-lasting remissions. Moreover, there is no…
4. 1. 2022 Source: Hematologic Malignancies
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