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Proposal of a New Treatment Sequence Algorithm for Heart Failure with Reduced Ejection Fraction

21. 2. 2022 Source: Heart Failure

John McMurray and Milton Packer published a proposal for a new treatment sequence algorithm for patients with heart failure with reduced ejection fraction (HFrEF) based on current findings in the 2021 issue of Circulation. This procedure consists of three steps and, according to the authors, should be initiated in patients who have achieved euvolemia through the use of diuretics.

kongresový sál řečník

Fresh from ASH 2021: Promising results of the combination of azacitidine with venetoclax and magrolimab in the treatment of AML

Dr. Naval Daver and his colleagues from the Anderson Cancer Center in Houston presented an oral report during the December congress of the American Society of Hematology (ASH 2021) about a phase…
17. 2. 2022 Source: Chronic Lymphocytic Leukemia
komplikace diabetu

How Diabetes Shortens Life or Mortality of Patients with Type 2 Diabetes

Type 2 diabetes mellitus (DM) has a significant impact on overall mortality across age categories. Who is most affected by this disease in terms of age and gender, and what are the current trends in…
17. 2. 2022 Source: Diabetes
generika_pilikly_krabička_léky

Less is Sometimes More –⁠ How Generic Substitution Can Affect Patient Adherence

It is undisputed that the use of generic drugs saves the healthcare system significant costs. Although doctors should certainly care about the health of the system, they primarily care for the health…
17. 2. 2022 Source: Modern Treatment of Diabetes
měření cukrovky

Limits of Glycated Hemoglobin and the Importance of Other Glycated Proteins

Glycated hemoglobin is a gold standard in the diagnosis and management of diabetes treatment. However, its disadvantages include numerous factors that can cause false increases or decreases in its…
17. 2. 2022 Source: Modern Treatment of Diabetes
žena_kašel

Treatment of Cough in Clinical Practice: Which Preparations Are Suitable and When?

In clinical practice, we differentiate the treatment of non-productive and moist productive cough. When choosing appropriate therapy, we consider the characteristics of the available medicinal…
15. 2. 2022 Source: Cough Therapy
Dítě_kašel

Quo vadis, erdostein? Or the current and future potential of erdosteine in practice

Erdosteine has a well-established place in the therapy of acute respiratory diseases in children. Its mucolytic and antibacterial properties are very well documented. Recently, research has focused…
15. 2. 2022 Source: Cough Therapy
dítě_plíce

What is the effectiveness of levodropropizine in the treatment of children's cough?

Levodropropizine represents an effective and safe option for the treatment of acute irritating cough in children. How does it compare to dropropizine and commonly used centrally acting antitussives?
15. 2. 2022 Source: Cough Therapy
Endometriosis

Effects of Progestins in Combination with EE on Endothelial Function, Lipid Levels, and Oxidative Stress in Women with Endometriosis

Studies have shown endothelial dysfunction and increased oxidative stress in women with endometriosis. Theoretically, they may be at increased cardiovascular risk. The study presented below…
15. 2. 2022 Source: Oral Contraception
alzheimer44

Alzheimer's Disease –⁠ Another Pandemic on the Horizon?

Due to the COVID-19 pandemic, other current problems often get pushed into the background. One of these is the aging population and the increasing prevalence of dementia. The key question thus…
11. 2. 2022 Source: Cognitive in the treatment of Alzheimer's disease
Léčba_rakovina_kapačka

Current Treatment Options for Multiple Myeloma

Multiple myeloma (MM) accounts for about 10% of all hematologic malignancies. Thanks to advancements in diagnostic methods, it is now understood as a collection of several cytologically distinct…
10. 2. 2022 Source: Hematologic Malignancies
pacient_lékař

In decisions about therapeutic strategy in multiple myeloma, patient preferences and concerns also play a crucial role

The perspective on the preferences of patients with multiple myeloma (MM) is very necessary at a time of rapid development of new treatment options. Patient priorities and their perception of…
10. 2. 2022 Source: Hematologic Malignancies
farmakologie farmakokinetika

Pharmacokinetic Comparison of Two EHL Products in Hemophilia A

According to a Canadian study published last year, certain pharmacokinetic differences were observed between two extended half-life factors.
8. 2. 2022 Source: Hemophilia
hypertenze léky

Efficacy and Safety of the Combination of Telmisartan and Amlodipine with Hydrochlorothiazide in the Treatment of Hypertension

The aim of the study by Korean authors was to evaluate the efficacy and tolerability of the triple combination of telmisartan/amlodipine + hydrochlorothiazide (TAH) compared to the combination of…
8. 2. 2022 Source: Sartans in the Treatment of Hypertension
nemocniční postel rozhovor lékaře s pacientem

Effect of Administering Ferric Carboxymaltose on Quality of Life in Heart Failure Patients

The quality of life in patients with heart failure is significantly reduced. The concurrent occurrence of iron deficiency further exacerbates this situation. The AFFIRM-AHF study evaluated the impact…
7. 2. 2022 Source: Iron Deficiency and Anemia
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