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Even in Severe Cases of HAE, Individualized Treatment is Crucial – Case Study
25. 2. 2022 Source: Hereditary AngioedemaAs part of the case seminar from the HAExpert series, held on December 1, 2021, which specifically focused on the treatment of hereditary angioedema (HAE) in specific patients, Dr. Roman Hakl from the Institute of Clinical Immunology and Allergology at MU Faculty of Medicine and St. Anne's University Hospital in Brno presented the case of a now 34-year-old woman with HAE and obesity (BMI 37 kg/m2), who additionally has a positive family history – the disease was also diagnosed in her mother, sister, and son.
Orally Administered Berotralstat in the Prevention of Hereditary Angioedema Attacks
Berotralstat is an oral medication administered once daily, developed to prevent hereditary angioedema (HAE) attacks. It is a kallikrein protease inhibitor, which plays a key role in the pathogenesis…25. 2. 2022 Source: Hereditary Angioedema
Current (and Future) Possibilities for Diagnosing Alpha-1-Antitrypsin Deficiency
Alpha-1-antitrypsin deficiency (AAT) is associated, among other things, with the development of chronic obstructive pulmonary disease (COPD) with emphysema. Most patients, however, remain undiagnosed…25. 2. 2022 Source: Deficiency of Alpha-1-Antitrypsin
How and What the National AATD Register Benefits Experts and Patients
Given that alpha-1-antitrypsin deficiency (AATD) is still not receiving enough attention, it is necessary to raise professional awareness of this hereditary disease by all means. This is also one of…25. 2. 2022 Source: Deficiency of Alpha-1-Antitrypsin
How and How the Czech National Hemophilia Program Benefits Professionals and Patients
The Czech National Hemophilia Program (ČNHP) has been an interdisciplinary initiative for many years, coordinating specialized care for both pediatric and adult patients with hemophilia and other…25. 2. 2022 Source: Von Willebrand Disease
Analgesic Effects of Using Ringer's Solution in Wound Healing Management
Pain resulting from skin defects of various etiologies causes significant discomfort for the patient. However, wound care using Ringer's solution and the use of primary dressings, which include this…25. 2. 2022 Source: Wound Healing
Wound Treatment Without Pain? A Rinse Solution Can Help
Patients dealing with a healing wound may fear painful dressing changes. The wound bed is exposed and highly sensitive to pain due to damaged nerve endings. By using a rinse solution, however, we can…25. 2. 2022 Source: Wound Healing
How to recognize amyloidosis as a cause of heart failure?
Although the fate of patients with heart failure has improved in recent decades, it remains a disease with a poor prognosis that significantly worsens the quality of life. The prevalence of heart…24. 2. 2022 Source: Amyloidosis
Inosine pranobex in the treatment of influenza and other respiratory infections of viral etiology
The antiviral inosine pranobex is a clinically proven immunomodulator for the treatment of patients from 1 year of age, indicated for a wide range of diseases with manifestations of immune…24. 2. 2022 Source: Viral infections
Maintaining Therapeutic Doses of Levothyroxine Throughout Shelf Life
Levothyroxine is the drug of choice for patients with hypothyroidism. However, it is also one of the substances with a narrow therapeutic range, which increases the risk of overdose or underdose,…23. 2. 2022 Source: Thyroid Disorders
Is there a link between Parvovirus B19 infection and autoimmune thyroid diseases?
Autoimmune thyroid diseases are among the most common autoimmune disorders, with a worldwide prevalence of around 10%. The study presented below, recently published in the International Journal of…23. 2. 2022 Source: Thyroid Disorders
Safety of Dabigatran in Secondary Prevention of Venous Thromboembolism in Pediatric Patients
Low molecular weight heparin (LMWH) or warfarin (VKA – vitamin K antagonist) is typically used for the secondary prevention of venous thromboembolism. The DIVERSITY study extension examined the…23. 2. 2022 Source: Anticoagulant Treatment
How to Dose Beta-Blockers After Myocardial Infarction?
In patients after myocardial infarction (MI), there is a frequent administration of too low doses of beta-blockers (BB) and rare upward titration of their dose after discharge from the hospital. The…23. 2. 2022 Source: Cardiovascular Continuum
How do patients perceive the change in appearance of chronically used medications and to what extent does it lead to non-adherence to therapy?
Doctors regularly encounter patients in their offices who complain about changes in the appearance of their chronically used medications. Such a change can even be the cause of non-adherence to…23. 2. 2022 Source: Cardiovascular Continuum
Analysis of the Benefits and Risks of Superabsorbent Dressings in the Treatment of Moderate to Highly Exuding Leg Ulcers
A study on the benefits and risks of superabsorbent dressings compared to standard dressings in the treatment of moderate to highly exuding leg ulcers was published last year in The International…22. 2. 2022 Source: Wound Healing
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