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The Importance of Limosilactobacillus reuteri in Administration to Diabetics with Gingivitis

10. 11. 2022 Source: GI, colic and microbiome

We summarize the results of a clinical study on the effect of probiotics containing Limosilactobacillus reuteri on the improvement of gingivitis in patients with diabetes. It has been proven that the supplementary administration of L. reuteri statistically significantly improves gum health and helps to suppress gingival inflammation.

Effectiveness of Compression Therapy in Patients with Leg Ulcers

Up to 2% of the population suffers from leg ulcers. The standard treatment for ulcers of venous etiology is compression. The following French study, whose results were recently published in the …

8. 11. 2022 Source: Wound Healing

Rurioctocog Alfa Pegol vs. Non-factor Therapy –⁠ Report from Real Clinical Practice

The standard treatment for hemophilia A is the prophylactic administration of coagulation factor VIII (FVIII) concentrate. Recently, some hemophiliacs have also been switched to prophylaxis with…

8. 11. 2022 Source: Hemophilia

Lorlatinib in a Patient with Meningeal Carcinomatosis –⁠ Case Report

The prognosis of patients with meningeal carcinomatosis is unfavorable. The following case report demonstrates how a targeted mechanism of action and optimal drug penetration into the central nervous…

6. 11. 2022 Source: Genetic Profile and Treatment of NSCLC

Tailored Treatment. Who is Teriflunomide Suitable For?

The authors of the recently published study cited below not only focused on the safety and efficacy of teriflunomide in real-world clinical practice but also on the risk factors for its insufficient…

3. 11. 2022 Source: Multiple Sclerosis

The Future of Multiple Sclerosis –⁠ Time for a Change in Classification?

What are the latest findings on the etiopathogenesis of multiple sclerosis? Are they reflected in the current classification? And what will future therapy look like?

3. 11. 2022 Source: Multiple Sclerosis

Protective Effect of SGLT2 Inhibitors on Heart Muscle Function -⁠ Findings from a Recent Meta-analysis

Sodium-glucose cotransporter 2 inhibitors (SGLT2i, i.e., gliflozins) primarily offer the ability to achieve very good glycemic control with a low risk of hypoglycemia. Their undeniable advantage,…

3. 11. 2022 Source: Heart Failure

Efficacy of Conventional and Intensified Lifestyle Interventions in Individuals with Prediabetes According to Risk Level

Lifestyle changes can prevent the development of type 2 diabetes in individuals with prediabetes, but according to current findings, these measures fail for a significant portion of study…

2. 11. 2022 Source: Modern Treatment of Diabetes

Metformin with Extended Release in the Treatment of Prediabetes

The benefit of metformin in preventing the development of diabetes in people with prediabetes has been demonstrated in clinical studies. However, these studies evaluated immediate-release metformin,…

2. 11. 2022 Source: Modern Treatment of Diabetes

Meta-analysis of the Metabolic Effects of Second-generation Antipsychotics

Second-generation antipsychotics used in the therapy of schizophrenia exhibit varying metabolic profiles. A recently conducted meta-analysis by Italian authors investigated the impact of…

1. 11. 2022 Source: Modern Treatment of Schizophrenia

Prevalence of Metabolic Syndrome During 1 Year After the First Episode of Psychosis

Portuguese authors elucidated the high prevalence of metabolic syndrome and adverse metabolic parameters in individuals with the first episode of psychosis. Moreover, it significantly increased…

1. 11. 2022 Source: Modern Treatment of Schizophrenia

How Does Erdosteine Perform in Combination with Antibiotics?

Erdosteine is an oral mucoactive drug that reduces mucus viscosity by degrading disulfide bonds in the mucin polymer. It achieves this effect through a free thiol group in its main active metabolite,…

1. 11. 2022 Source: Cough Therapy

Benefit of Adding Erdosteine to Maintenance Treatment of COPD

Erdosteine is a mucoactive drug with anti-inflammatory, antioxidant, and anti-adhesive effects against bacteria, commonly used in the treatment of chronic obstructive pulmonary disease (COPD). In…

1. 11. 2022 Source: Cough Therapy

ERS 2022: What Insights Do Studies Focused on COPD Biomarkers Bring?

In this year's scientific program of the international congress of the European Respiratory Society (ERS 2022), there was also a lot of talk about the investigation of biomarkers of chronic…

1. 11. 2022 Source: Cough Therapy

Specific treatment of pulmonary involvement in patients with AAT deficiency −⁠ why, how, and for whom?

For patients with emphysema and decreased lung function due to alpha-1-antitrypsin deficiency (AATD), there is an approved specific treatment which involves the i.v. administration of…

1. 11. 2022 Source: Deficiency of Alpha-1-Antitrypsin

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