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The Importance of Proper Protein and Calorie Intake in Critically Ill Patients –⁠ Insights from Recent Comparisons

14. 11. 2022 Source: Parenteral Nutrition

The issue of nutrition, especially proteins, is a crucial aspect affecting the overall health and prognosis of critically ill patients. Two recent studies published in the journals Critical Care and Journal of Parenteral and Enteral Nutrition focused on nutrient intake.

Impact of Early Administration of High Protein Dose on Mortality of Critically Ill Patients

Energy intake and the composition of individual macronutrients in patients in intensive care units (ICUs) can influence treatment outcomes in terms of the incidence of complications, duration of…

14. 11. 2022 Source: Parenteral Nutrition

MDT Board: a unique project for doctors caring for patients with lung diseases and other thoracic pathologies

A unique concept of a cooperative thoracic group has been created in the Czech Republic, involving specialists from several leading Prague clinics. The primary purpose of the so-called board is to…

14. 11. 2022 Source: MDT Board

Population Pharmacokinetic Model in Patients with von Willebrand Disease

Dutch authors presented a potential population pharmacokinetic model describing levels of von Willebrand factor and coagulation factor VIII during and after surgical procedures in patients with von…

14. 11. 2022 Source: Von Willebrand Disease

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Pharmacokinetics of Concentrates for the Treatment of von Willebrand’s Disease

Von Willebrand's disease (vWD) is characterized by a deficiency or reduced functional capacity of von Willebrand factor (vWF) and, in more severe cases, by a deficiency of coagulation factor VIII…

14. 11. 2022 Source: Von Willebrand Disease

New Therapeutic Options in Light of Current Knowledge on the Pathogenesis of Atopic Dermatitis

Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by intense itching and recurrent eczematous lesions. AD is diagnosed in 2 out of 10 children and often persists into…

14. 11. 2022 Source: Biological Treatment

Potential of Aloe to Reduce Severity of Symptoms in Patients with IBS −⁠ What Emerged from the Analysis of Fecal Microflora and Metabolite Profiles?

Current treatment options for irritable bowel syndrome (IBS −⁠ irritable bowel syndrome) are relatively limited. This increases interest in complementary and alternative therapy options with plant…

12. 11. 2022 Source: Irritable Bowel Syndrome

ESC 2022: SGLT2 Inhibitors as Hope for HFpEF: How to Implement Them in Practice?

Patients with heart failure (HF) can significantly benefit from the inclusion of sodium-glucose co-transporter 2 inhibitors (SGLT2i, i.e., gliflozins) in their treatment strategy according to current…

10. 11. 2022 Source: Heart Failure

The Importance of Limosilactobacillus reuteri in Administration to Diabetics with Gingivitis

We summarize the results of a clinical study on the effect of probiotics containing Limosilactobacillus reuteri on the improvement of gingivitis in patients with diabetes. It has been proven that the…

10. 11. 2022 Source: GI, colic and microbiome

Effectiveness of Compression Therapy in Patients with Leg Ulcers

Up to 2% of the population suffers from leg ulcers. The standard treatment for ulcers of venous etiology is compression. The following French study, whose results were recently published in the …

8. 11. 2022 Source: Wound Healing

Rurioctocog Alfa Pegol vs. Non-factor Therapy –⁠ Report from Real Clinical Practice

The standard treatment for hemophilia A is the prophylactic administration of coagulation factor VIII (FVIII) concentrate. Recently, some hemophiliacs have also been switched to prophylaxis with…

8. 11. 2022 Source: Hemophilia

Lorlatinib in a Patient with Meningeal Carcinomatosis –⁠ Case Report

The prognosis of patients with meningeal carcinomatosis is unfavorable. The following case report demonstrates how a targeted mechanism of action and optimal drug penetration into the central nervous…

6. 11. 2022 Source: Genetic Profile and Treatment of NSCLC

Tailored Treatment. Who is Teriflunomide Suitable For?

The authors of the recently published study cited below not only focused on the safety and efficacy of teriflunomide in real-world clinical practice but also on the risk factors for its insufficient…

3. 11. 2022 Source: Multiple Sclerosis

The Future of Multiple Sclerosis –⁠ Time for a Change in Classification?

What are the latest findings on the etiopathogenesis of multiple sclerosis? Are they reflected in the current classification? And what will future therapy look like?

3. 11. 2022 Source: Multiple Sclerosis

Protective Effect of SGLT2 Inhibitors on Heart Muscle Function -⁠ Findings from a Recent Meta-analysis

Sodium-glucose cotransporter 2 inhibitors (SGLT2i, i.e., gliflozins) primarily offer the ability to achieve very good glycemic control with a low risk of hypoglycemia. Their undeniable advantage,…

3. 11. 2022 Source: Heart Failure

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