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Dosing and Consumption of rFVIII Products with Extended Half-life in Patients with Hemophilia A in Real-World Practice
Based on real-world data from the USA, a recently published study compared two recombinant human factor VIII (rFVIII) products with extended half-life (EHL) – efmoroctocog alfa and rurioctocog alfa pegol, in terms of dosing frequency, weekly consumption, and dose variability.
Ligamentous Changes as a Harbinger of Cardiac Amyloidosis – Histopathological and Clinical Study
Amyloid deposits can be present in various types of tissue. Their accumulation in connective tissue…
AAD 2023: Efficacy of Bimekizumab in the Treatment of Hidradenitis Suppurativa
At the latest annual congress of the American Academy of Dermatology (AAD), held March 17-22, 2023…
Efficacy and Safety of Ultrahypofractionated Proton Therapy in the Treatment of Prostate Cancer in Real-World Czech Practice
A team from the Prague Proton Therapy Center, led by Associate Professor Jiří Kubeš, published a…
Genetic Testing in Clinical Practice – An Irreplaceable Tool in Prevention, Diagnosis and Treatment
Genetic testing has long ceased to be the privilege of clinical research. In practice, it is commonly...
What Lies Behind ChatGPT? Artificial Intelligence with Potential Use Even in Clinical Medicine
ChatGPT, a program that enables conversation with sophisticated 'artificial intelligence', or…
Subcutaneous Immunoglobulin Substitution in Ig-Naive Patients with PID – Available Efficacy and Safety Data
The prevalence of primary immunodeficiencies (PID) is estimated at 1:10,000. Below, we summarize…
Bimekizumab in the Treatment of Psoriasis After Failure of (Not Only) Anti-IL-17A Antibodies – Case Reports
German authors last year described the first 2 cases of patients with psoriasis in whom treatment…
Metamizole in Pain Therapy in the General Practitioner and Pediatric Office
Metamizole is a pyrazole analgesic-antipyretic with spasmolytic effects, indicated for the…
Non-Steroidal Anti-Inflammatory Drugs in the Treatment of Ankylosing Spondylitis: Network Meta-Analysis
A literature review and network meta-analysis of randomized controlled trials published in the…