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Persistent Symptom Control with s.c. Supplementation of C1 Inhibitor in Prophylactic Treatment of HAE

14. 11. 2022 Source: Hereditary Angioedema

The open-label extension of the COMPACT study with subcutaneous C1 inhibitor in the prophylaxis of hereditary angioedema (HAE) has brought fresh results, shedding light on the treatment's impact on the frequency of attacks and reducing the need for rescue medication.

Inhibitor of Activated Factor XII Garadacimab in Prophylaxis of HAE Attacks

Hereditary angioedema (HAE) is an autosomal dominant inherited disease characterized by a deficiency of C1 inhibitor. This condition leads to excessive production of bradykinin, which is responsible…

14. 11. 2022 Source: Hereditary Angioedema

Good news for sleep in patients with axial spondyloarthritis –⁠ ixekizumab effectively reduces night-time back pain

The targeted treatment of axial spondyloarthritis currently relies on the anti-inflammatory effects of tumor necrosis factor (TNF) inhibitors, interleukin IL-17 inhibitors, and Janus kinase (JAK)…

14. 11. 2022 Source: Biological Treatment

Two Current Perspectives on the Importance of (Par)enteral Nutrition in Cancer Patients

Adequate (par)enteral nutrition is crucial for cancer patients in terms of prognosis and quality of life. The following recent studies examined parenteral nutrition as an alternative to ileostomy in…

14. 11. 2022 Source: Parenteral Nutrition

To what extent can improvement of nutritional status through parenteral nutrition affect the results of oncological treatment?

Just like cancer patients and their caregivers, doctors often overlook the risk of malnutrition. Good nutrition can be a predictor of survival in patients with malignancies.

14. 11. 2022 Source: Parenteral Nutrition

Does SGLT2 Inhibitor Administration Benefit Diabetics with Low Cardiorenal Risk?

There is growing evidence of the cardiorenal protective effects of sodium-glucose cotransporter 2 inhibitors (SGLT2i, also known as gliflozins), which were developed as antihyperglycemic drugs for…

14. 11. 2022 Source: Diabetes

6 Possible Benefits of Adding Empagliflozin to Metformin

Currently, there is intense discussion about the advantages of sodium-glucose co-transporter 2 inhibitors (SGLT2i, also known as gliflozins) in terms of their cardio and nephroprotective properties.…

14. 11. 2022 Source: Diabetes

The Importance of Proper Protein and Calorie Intake in Critically Ill Patients –⁠ Insights from Recent Comparisons

The issue of nutrition, especially proteins, is a crucial aspect affecting the overall health and prognosis of critically ill patients. Two recent studies published in the journals Critical Care and …

14. 11. 2022 Source: Parenteral Nutrition

Impact of Early Administration of High Protein Dose on Mortality of Critically Ill Patients

Energy intake and the composition of individual macronutrients in patients in intensive care units (ICUs) can influence treatment outcomes in terms of the incidence of complications, duration of…

14. 11. 2022 Source: Parenteral Nutrition

MDT Board: a unique project for doctors caring for patients with lung diseases and other thoracic pathologies

A unique concept of a cooperative thoracic group has been created in the Czech Republic, involving specialists from several leading Prague clinics. The primary purpose of the so-called board is to…

14. 11. 2022 Source: MDT Board

Population Pharmacokinetic Model in Patients with von Willebrand Disease

Dutch authors presented a potential population pharmacokinetic model describing levels of von Willebrand factor and coagulation factor VIII during and after surgical procedures in patients with von…

14. 11. 2022 Source: Von Willebrand Disease

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Pharmacokinetics of Concentrates for the Treatment of von Willebrand’s Disease

Von Willebrand's disease (vWD) is characterized by a deficiency or reduced functional capacity of von Willebrand factor (vWF) and, in more severe cases, by a deficiency of coagulation factor VIII…

14. 11. 2022 Source: Von Willebrand Disease

New Therapeutic Options in Light of Current Knowledge on the Pathogenesis of Atopic Dermatitis

Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by intense itching and recurrent eczematous lesions. AD is diagnosed in 2 out of 10 children and often persists into…

14. 11. 2022 Source: Biological Treatment

Potential of Aloe to Reduce Severity of Symptoms in Patients with IBS −⁠ What Emerged from the Analysis of Fecal Microflora and Metabolite Profiles?

Current treatment options for irritable bowel syndrome (IBS −⁠ irritable bowel syndrome) are relatively limited. This increases interest in complementary and alternative therapy options with plant…

12. 11. 2022 Source: Irritable Bowel Syndrome

ESC 2022: SGLT2 Inhibitors as Hope for HFpEF: How to Implement Them in Practice?

Patients with heart failure (HF) can significantly benefit from the inclusion of sodium-glucose co-transporter 2 inhibitors (SGLT2i, i.e., gliflozins) in their treatment strategy according to current…

10. 11. 2022 Source: Heart Failure

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