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Metamizole as an Analgesic with a Favorable Benefit-Risk Ratio
29. 3. 2023 Source: AnalgesiaMetamizole is a well-established and widely used molecule in many countries worldwide, suitable as an alternative to opioids for patients with moderate to severe acute or chronic pain. The popularity of this drug is associated not only with its efficacy but also with its safety, with no contraindications for patients with cardiovascular, renal, or gastrointestinal comorbidities.
Doc. Jitka Fricová: The biggest challenge remains the patient with unbearable chronic pain
Research findings are pushing the boundaries of optimal chronic pain treatment, including better prevention and reduced side effects of analgesics. Algological care is readily accessible in the Czech…29. 3. 2023 Source: Analgesia
The main advantage of sartans is a very good safety profile. Now it is about increasing adherence in hypertensive patients
The rules for initiating hypertension treatment have been simplified. The trend is to achieve blood pressure control as early as possible, making it unnecessary to wait for a longer period for the…28. 3. 2023 Source: Sartans in the Treatment of Hypertension
Beta-blockers in the treatment of chronic heart failure: How did the analysis of the effects of 4 drugs in 26 studies turn out?
As a cornerstone of therapy for chronic heart failure with reduced ejection fraction (HFrEF), it is recommended to start treatment with a very low dose of beta-blockers (BB) and titrate it to the…28. 3. 2023 Source: Cardiovascular Continuum
Efficacy of Bisoprolol in Patients After Acute MI with LV Systolic Dysfunction
What impact does one year of bisoprolol use have in real-world practice on heart rate, left ventricular ejection fraction (LVEF), glycated hemoglobin (HbA1c) levels, or lipid profile in patients…27. 3. 2023 Source: Cardiovascular Continuum
INFOGRAPHIC: How does liposomal ozonized oil work in treating eye infections?
Ozonized sunflower oil exhibits antimicrobial, anti-inflammatory, and healing properties, which is why it is added to eye drops intended for infection prevention. We bring you a clear schematic of…24. 3. 2023 Source: Treatment of Glaucoma
Liposomal Ozonated Oil in the Treatment of Eye Infections
Liposomal ozonated oil is a new ocular antiseptic with antibacterial, anti-inflammatory, and regenerative properties, making it suitable for the prevention and treatment of eye infections and as an…24. 3. 2023 Source: Treatment of Glaucoma
H₂FPEF Score for Estimating the Probability of Heart Failure with Preserved Ejection Fraction in Persons with Unexplained Dyspnea
The simple, validated H₂FPEF scoring system based on clinical and echocardiographic parameters, developed by experts from the Mayo Clinic, allows the differentiation of heart failure with preserved ejection...23. 3. 2023 Source: Heart Failure
“Smart” Bra as a Helper in Breast Cancer Detection
Malignant breast tumors represent one of the most common oncological diseases in women worldwide. For improving patient prognosis, it is crucial to detect the disease in its early, curable stages. In…23. 3. 2023 Source: medScope.pro
What a General Practitioner Needs to Know About Gliflozins
The revolutionary benefits of gliflozins have completely changed the perspective on the choice of pharmacotherapy for diabetes. They have attracted not only diabetologists but also cardiologists and…22. 3. 2023 Source: Diabetes
Results of Long-Term Follow-Up of Patients with Prostate Adenocarcinoma After Radiotherapy with Short-Term Androgen Deprivation
Adding short-term androgen deprivation to radiotherapy improved overall survival, disease-specific mortality, and the incidence of distant metastases in men diagnosed with prostate adenocarcinoma.…21. 3. 2023 Source: Oncological Treatment
Longer survival without liver transplant in patients with PBC treated with OCA?
Obeticholic acid (OCA) is a second-line treatment for patients with primary biliary cholangitis (PBC) who have an inadequate response to ursodeoxycholic acid (UDCA) or intolerance to it. The study…20. 3. 2023 Source: Primary Biliary Cholangitis
Dressing Solutions for Better Wound Care
Although wounds at different stages of healing require different types of treatment, the essential part of any dressing change is cleaning the wound and its surroundings from tissue debris and…19. 3. 2023 Source: Wound Healing
Care of Surgical Wounds and Choice of Dressings − Main Findings of the Latest International Expert Consensus
In December 2022, Wounds International published a summary of consensus outputs from six international expert meetings dedicated to postoperative care of surgical wounds and the selection of their…19. 3. 2023 Source: Wound Healing
Impact of Comorbidities on the Efficacy of Ceftaroline Fosamil in Complicated Skin and Soft Tissue Infections − Pooled Analysis of 3 Studies
In 3 randomized Phase III studies, ceftaroline fosamil demonstrated non-inferiority in treating complicated skin and soft tissue infections (cSSTI) compared to vancomycin + aztreonam. A recent pooled…17. 3. 2023 Source: Anti-Infectives
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