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kojící pacientka

Diagnosis and Management of Therapy for a Breastfeeding Patient with Significant Elevation of Liver Enzymes Postpartum –⁠ Interactive Case Study

14. 4. 2023 Source: Primary Biliary Cholangitis

In the following case study, we present a specific approach to a patient who developed a significant elevation of liver enzymes after childbirth. Through interactive elements, you can try out how you would proceed in diagnosing and treating this case.

Empagliflozin

Empagliflozin will be funded from May for symptomatic heart failure regardless of EF LK value

Empagliflozin entered the market as an antidiabetic drug operating on the principle of reducing glucose reabsorption by the kidneys from the urine and increasing its excretion through urine. Thanks…
14. 4. 2023 Source: Heart Failure
Closeup růžovo-bílá a modro-bílá antibiotika kapsle

Current View on Obstacles in Proper Use of Antibiotics and the Role of Biomarkers in Infection Diagnosis

In the fight against antibiotic resistance, principles for the proper use of antibiotics (ATB) have been introduced globally. The following overview briefly describes the obstacles in leading…
13. 4. 2023 Source: Anti-Infectives
Screening plic

Screenings of Lung Cancer and COPD are Significant. What Do the Latest Data from Czechia Say?

At the end of January, an expert seminar was held, focusing on updates in the treatment of respiratory diseases. During this event, the head of the Pulmonary Clinic at LF UK and FN Hradec Králové, …
12. 4. 2023 Source: Cough Therapy
subkutánní_injekce_břicho

Measurement of Serum Trough Levels of IgG as an Adequate and Beneficial Indicator for Assessing the Pharmacokinetics of Subcutaneously Administered Products

For many patients with primary immunodeficiency, lifelong immunoglobulin substitution is essential to reduce the frequency of severe infections. Subcutaneous home administration is better accepted by...
11. 4. 2023 Source: Primary and Secondary Immunodeficiencies
hemofilie výzkum krve

Dosing and Consumption of rFVIII Products with Extended Half-life in Patients with Hemophilia A in Real-World Practice

Based on real-world data from the USA, a recently published study compared two recombinant human factor VIII (rFVIII) products with extended half-life (EHL) –⁠ efmoroctocog alfa and rurioctocog alfa…
11. 4. 2023 Source: Hemophilia
syndrom karpálního tunelu

Ligamentous Changes as a Harbinger of Cardiac Amyloidosis –⁠ Histopathological and Clinical Study

Amyloid deposits can be present in various types of tissue. Their accumulation in connective tissue can lead to pathological changes resulting in the rupture of stressed structures (e.g., the…
10. 4. 2023 Source: Amyloidosis
hidradenitis suppurativa

AAD 2023: Efficacy of Bimekizumab in the Treatment of Hidradenitis Suppurativa

At the latest annual congress of the American Academy of Dermatology (AAD), held March 17-22, 2023 in New Orleans, the results of the phase III BE HEARD I and II studies were presented among …
7. 4. 2023 Source: Psoriasis
karcinom prostaty

Efficacy and Safety of Ultrahypofractionated Proton Therapy in the Treatment of Prostate Cancer in Real-World Czech Practice

A team from the Prague Proton Therapy Center, led by Associate Professor Jiří Kubeš, published a study with nearly 300 patients in the prestigious International Journal of Radiation Oncology,…
5. 4. 2023 Source: Proton Radiotherapy
genetika a testovani

Genetic Testing in Clinical Practice –⁠ An Irreplaceable Tool in Prevention, Diagnosis and Treatment

Genetic testing has long ceased to be the privilege of clinical research. In practice, it is commonly used for screening, diagnosis, and prognosis determination in diseases with an evident genetic component,...
4. 4. 2023 Source: Genetics
Umělá inteligence

What Lies Behind ChatGPT? Artificial Intelligence with Potential Use Even in Clinical Medicine

ChatGPT, a program that enables conversation with sophisticated 'artificial intelligence', or rather an algorithm based on machine learning, is currently a huge hit. However, it represents just the…
4. 4. 2023 Source: medScope.pro
dokumenty

Subcutaneous Immunoglobulin Substitution in Ig-Naive Patients with PID –⁠ Available Efficacy and Safety Data

The prevalence of primary immunodeficiencies (PID) is estimated at 1 : 10,000. Below, we summarize the available findings on the efficacy and safety of subcutaneous immunoglobulin substitution in…
3. 4. 2023 Source: Primary and Secondary Immunodeficiencies
psoriaza dite tvar

Bimekizumab in the Treatment of Psoriasis After Failure of (Not Only) Anti-IL-17A Antibodies –⁠ Case Reports

German authors last year described the first 2 cases of patients with psoriasis in whom treatment with, among other things, anti-IL-17A antibodies failed, but who responded to the blockade of…
2. 4. 2023 Source: Psoriasis
Metamizol_léky

Metamizole in Pain Therapy in the General Practitioner and Pediatric Office

Metamizole is a pyrazole analgesic-antipyretic with spasmolytic effects, indicated for the treatment of post-traumatic or postoperative pain, visceral colic, cancer pain, and high fever unresponsive…
30. 3. 2023 Source: Updates in Pain Treatment
ankylozující spondylitida

Non-Steroidal Anti-Inflammatory Drugs in the Treatment of Ankylosing Spondylitis: Network Meta-Analysis

A literature review and network meta-analysis of randomized controlled trials published in the journal Experimental and Therapeutic Medicine demonstrates the high efficacy and good tolerability of 6…
30. 3. 2023 Source: Updates in Pain Treatment
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