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Nucleic Acid Amplification Tests in the Diagnosis of Sexually Transmitted Diseases
28. 6. 2023 Source: GeneticsBased on 81 scientific papers published between 2010 and 2021, experts from Johns Hopkins University in Baltimore have prepared an overview of the current epidemiology, diagnosis, and treatment of sexually transmitted diseases (STD). We summarize information on the diagnosis of gonorrhea, chlamydial infections, M. genitalium, trichomoniasis, genital infections by HSV-1/2, and HPV using nucleic acid amplification tests (NAAT), the most well-known method being PCR. NAAT shows high sensitivity and specificity in testing for these diseases.
How to Reduce the Risk of Venous Thromboembolism in Users of Combined Hormonal Contraceptives?
The use of combined oral contraceptives (COCs) is a known risk factor for thromboembolism.…27. 6. 2023 Source: Genetics
Deficit dihydropyrimidine dehydrogenase and its association with 5-fluorouracil toxicity
Deficit dihydropyrimidine dehydrogenase (DPD) is a risk factor for severe toxicity of…12. 6. 2023 Source: Genetics
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CYP Enzyme? Cytochrome P450 2D6 and Drug Metabolism
The CYP2D6 isoenzyme of cytochrome P450 participates in the metabolism of approximately 20% of...5. 5. 2023 Source: Genetics
Association of M2 Haplotype of the Annexin A5 Gene with Recurrent Reproductive Losses
Annexin A5 (ANXA5) is a placental anticoagulant protein that ensures adequate blood supply to…5. 5. 2023 Source: Genetics
Etiology of Recurrent Reproductive Losses – Focus on Genetics
Repeated pregnancy losses pose a significant threat to a woman's physical and mental health.…4. 5. 2023 Source: Genetics
Li-Fraumeni Syndrome – Indication for Testing and Recommended Surveillance
A germline mutation of the TP53 gene, which causes Li-Fraumeni syndrome, results in a congenital...3. 5. 2023 Source: Genetics
Genetic Testing in Clinical Practice – An Irreplaceable Tool in Prevention, Diagnosis and Treatment
Genetic testing has long ceased to be the privilege of clinical research. In practice, it is commonly...4. 4. 2023 Source: Genetics
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Most read on this topic- Association of M2 Haplotype of the Annexin A5 Gene with Recurrent Reproductive Losses
- Deficit dihydropyrimidine dehydrogenase and its association with 5-fluorouracil toxicity
- How to Reduce the Risk of Venous Thromboembolism in Users of Combined Hormonal Contraceptives?
- Genetic Testing in Clinical Practice – An Irreplaceable Tool in Prevention, Diagnosis and Treatment
- Etiology of Recurrent Reproductive Losses – Focus on Genetics
- CYP Enzyme? Cytochrome P450 2D6 and Drug Metabolism
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