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Augmentation Therapy of Bronchiectasis Due to AATD –⁠ Case Report

26. 4. 2023 Source: Deficiency of Alpha-1-Antitrypsin

Alpha-1-antitrypsin deficiency (AATD) is a rare cause of bronchiectasis unrelated to cystic fibrosis. The role of augmentation therapy with alpha-1-antitrypsin (AAT) in patients with AATD with bronchiectasis without pulmonary emphysema is still unclear. A case report from authors in Heidelberg presents a patient with bronchiectasis based on AATD, where augmentation therapy reduced the number of exacerbations and improved clinical condition.

Pregnancy and Childbirth in a Woman with VWD −⁠ A Case Study

Pregnancy and childbirth are relatively demanding periods and situations for women with von Willebrand disease (vWD) from the perspective of hemostasis. They can be associated with an increased risk of...

26. 4. 2023 Source: Von Willebrand Disease

Benefits and Cost-Effectiveness of Superabsorbent Dressings in the Treatment of Venous Leg Ulcers

A recent cost-effectiveness analysis based on German data showed that using superabsorbent dressings instead of conventional dressings in the treatment of venous leg ulcers with moderate to high…

26. 4. 2023 Source: Wound Healing

Brain implants can affect the human mind in a surprising way

The technology company Neuralink, owned by Elon Musk, announced in December 2022 that it plans to start clinical testing of an electronic chip to be implanted in the skull within six months. However,…

26. 4. 2023 Source: medScope.pro

Absorption of Levothyroxine: What Has the New Formulation of LT4-Containing Medicinal Products Brought?

Lifelong use of levothyroxine (LT4) is the cornerstone of hypothyroidism treatment. The narrow therapeutic range of LT4 places increased emphasis on accurate dosing and appropriate titration, making…

26. 4. 2023 Source: Thyroid Disorders

What situations can arise in PBC treatment with obeticholic acid? Answers provided by case studies from real practice at CKTCH

The Hradec Gastroenterology Days 2023 were traditionally held in March at the Educational Center of the Faculty of Medicine, Charles University, in the area of University Hospital Hradec Králové. The…

25. 4. 2023 Source: Primary Biliary Cholangitis

Subclinical Hypothyroidism in Pregnancy: How Great Are the Real Risks and Can They Be Effectively Reduced?

The aim of the meta-analysis by authors from the Mayo Clinic was to describe the impact of subclinical hypothyroidism on the course of pregnancy and the effect of levothyroxine replacement therapy in…

25. 4. 2023 Source: Thyroid Disorders

Adherence to Treatment of Multiple Sclerosis: How to Enhance It and What Interesting Insights Emerged from Current Research?

Therapeutic options for patients with multiple sclerosis (MS) utilizing disease-modifying drugs (DMDs) have continued to expand in recent years. However, achieving their full benefit is critically dependent...

24. 4. 2023 Source: Multiple Sclerosis

Teriflunomide in the Treatment of RRMS: The Best Working Drug Is the One That the Patient Actually Takes

Teriflunomide is an oral disease-modifying drug (DMD) used in the therapy of relapsing-remitting multiple sclerosis (RRMS). The authors of the cited American study assessed adherence to this treatment...

24. 4. 2023 Source: Multiple Sclerosis

Early Tumor Regression as a Marker of Overall Survival in First-Line Treatment of mCRC

In the treatment of metastatic colorectal cancer (mCRC), prognostic factors besides overall survival (OS) and progression-free survival (PFS) include early tumor regression (ETS) and depth of…

21. 4. 2023 Source: Colorectal Cancer

Meta-Analysis of the Results of Studies Comparing the Effectiveness of Manual and Sonic Toothbrushes

Brushing teeth is a fundamental means of maintaining good oral hygiene. While many people still rely on using manual toothbrushes, brushing with electric toothbrushes has also gradually gained…

21. 4. 2023 Source: Dental Care

Is Obesity a Universal Phenotype in Children with Type 2 Diabetes?

What is the global prevalence of obesity in children and adolescents suffering from type 2 diabetes mellitus (T2DM)? Does the occurrence of obesity in pediatric T2DM correlate with gender or race?…

19. 4. 2023 Source: Modern Treatment of Diabetes

Echocardiography in the Diagnosis of Cardiac Amyloidosis

Cardiac amyloidosis remains a diagnostic challenge that requires great clinical vigilance. The imaging method of choice for evaluating heart failure suspected of amyloidosis is echocardiography. What…

17. 4. 2023 Source: Amyloidosis

Diagnosis and Management of Therapy for a Breastfeeding Patient with Significant Elevation of Liver Enzymes Postpartum –⁠ Interactive Case Study

In the following case study, we present a specific approach to a patient who developed a significant elevation of liver enzymes after childbirth. Through interactive elements, you can try out how you...

14. 4. 2023 Source: Primary Biliary Cholangitis

Empagliflozin will be funded from May for symptomatic heart failure regardless of EF LK value

Empagliflozin entered the market as an antidiabetic drug operating on the principle of reducing glucose reabsorption by the kidneys from the urine and increasing its excretion through urine. Thanks…

14. 4. 2023 Source: Heart Failure

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