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How does empagliflozin perform in older type 2 diabetics compared to liraglutide and sitagliptin in terms of HHF and MACE risks?

28. 8. 2023 Source: Diabetes

Last fall, a study was published in JAMA Network Open, focusing on older patients with type 2 diabetes mellitus (DM2), examining the cardiovascular risk impact when treated with empagliflozin, liraglutide, or sitagliptin. Currently, there is limited evidence comparing the effectiveness of various glucose-lowering agents intended for second-line treatment in DM2 patients undergoing routine care, who have a broad spectrum of cardiorenal risks.

vakcina dite naplast

Prof. Roman Chlíbek: Role of Multivalent Pneumococcal Conjugate Vaccines in Healthy and Premature Children

Children are frequent carriers of pneumococci, which can cause both common non-invasive and more…
25. 8. 2023 Source: Regular Vaccination
nemocnice

Hereditary Angioedema as a Clinical Picture of Excessive Activation of the Kinin Cascade – Case Report

Painful and potentially life-threatening swellings are characteristic of hereditary angioedema…
25. 8. 2023 Source: Hereditary Angioedema
Měření ejekční frakce

Efficacy of Empagliflozin in HFpEF Patients – Comparison of Subpopulations with Preserved and Mid-Range LV EF

A sub-analysis of the EMPEROR-Preserved clinical trial examined the effects and safety of…
24. 8. 2023 Source: Heart Failure
artritida cislo 1

EULAR 2023: How does tofacitinib affect cardiovascular risk in rheumatoid arthritis?

At this year's European League Against Rheumatism (EULAR) congress, held at the turn of May and…
23. 8. 2023 Source: Arthritis
Ceftazidim/avibaktam (CZA)1

Efficacy of Ceftazidime/Avibactam in the Treatment of Infections Caused by Carbapenemase-Producing Enterobacteria

Infections caused by carbapenemase-producing enterobacteria are associated with high mortality, and…
22. 8. 2023 Source: Anti-Infectives
artritida cislo 2

EULAR 2023: What Do CRP Levels Reveal About the Efficacy and Safety of Tofacitinib in Patients with Ankylosing Spondylitis?

What is the impact of baseline C-reactive protein (CRP) levels on the efficacy and safety of…
22. 8. 2023 Source: Arthritis
uceloznikolitida

Long-term treatment of ozanimod in patients with moderate to severe ulcerative colitis

The immunosuppressive ozanimod was approved for the treatment of ulcerative colitis (UC) based on…
21. 8. 2023 Source: Modulation of S1P in the Treatment of Autoimmune Diseases
Nefrotiliáza - bolest pacienta

Can SGLT2 Inhibition Also Reduce the Risk of Nephrolithiasis?

Diabetes mellitus (DM) is a risk factor for the development of nephrolithiasis. Recent studies…
21. 8. 2023 Source: Diabetes
roztrousenaskleroza_mozek

MS in the Digital Age: Doctor as a Lifebuoy in the Sea of Information

How to offer a helping hand to patients amidst the flood of information and why is communication…
15. 8. 2023 Source: Multiple Sclerosis
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