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Prostate Health Index and its Possible Use in Clinical Practice

9. 11. 2020 Source: Prostate Health Index

With the increasing incidence of prostate cancer, the effort to improve its diagnostics is also growing. The exclusively used and practice-proven prostate-specific antigen (PSA) continues to play an indispensable role in identifying at-risk patients, but some of its isoforms can also provide important information for deciding the patient's further fate. Based on their combination, a so-called prostate health index (PHI) can be determined. A recently published work by Czech authors assessed the usability of PHI as a parameter suitable for…

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Levothyroxine and the Interchangeability of Preparations Containing It

Levothyroxine is a synthetic thyroid hormone used to treat patients with hypothyroidism, which affects approximately 1-2% of the younger population and increases with age, especially in women.…
6. 11. 2020 Source: Thyroid Disorders
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Desirable Side Effects of Antidiabetics

The days when diabetology was a field solely focused on normalizing blood sugar levels are long gone. Today, the approach in diabetology increasingly prioritizes influencing the patient's overall…
6. 11. 2020 Source: Diabetes
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Benefit of a single intra-articular injection of hyaluronic acid in the treatment of osteoarthritis

Viscosupplementation serves as a minimally invasive procedure to restore the rheological properties of synovial fluid and alleviate pain in patients with symptomatic osteoarthritis (OA). We now have…
6. 11. 2020 Source: Osteoarthritis
Injekce a biologická léčba

Efficacy and Safety of Single-Application Hyaluronic Acid in Osteoarthritis Therapy

Causal therapy for osteoarthritis does not yet exist. Patients suffering from progressive joint disease are thus dependent on symptomatic medications that alleviate symptoms and partially slow the…
6. 11. 2020 Source: Osteoarthritis
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Enoxaparin in Weight-Based Dosing for Thromboprophylaxis in Hospitalized Cancer Patients

Cancer patients are at higher risk of developing thromboembolic disease during hospitalization. Currently, there is not enough evidence supporting the efficacy and safety of the standard fixed dose…
6. 11. 2020 Source: Thromboprophylaxis

Neoadjuvant Immunotherapy in Resectable Non-Small Cell Lung Cancer

Antibodies against the programmed cell death protein 1 (PD-1) improve the survival of patients with advanced non-small cell lung cancer (NSCLC). However, their use has not yet been tested in patients…
6. 11. 2020 Source: Immunotherapy in Oncology
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Impact of Alpha-1 Antitrypsin Deficiency on Quality of Life and Mental Health of Patients

The clinical manifestation of alpha-1 antitrypsin deficiency and its impact on quality of life are highly heterogeneous. This contribution by pulmonologist Robert Sandhaus summarizes interesting…
3. 11. 2020 Source: Deficiency of Alpha-1-Antitrypsin
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COVID-19 and Immune Thrombocytopenic Purpura −⁠ Spanish Experience Suggests Surprising Connections

In a retrospective study examining the impact of COVID-19 on immune thrombocytopenic purpura, Spanish authors surprisingly observed a paradoxical effect.
2. 11. 2020 Source: Immune Thrombocytopenia
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Care of Dental Dentures According to the Recommendations of the American Society of Dental Prosthetists

Dental dentures are the most common solution for missing teeth in the jaw. They should serve patients for several years, so proper care is essential. Therefore, dental professionals should not only…
2. 11. 2020 Source: Optimal Care of Dentures
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