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Topically administered tacrolimus does not increase cancer risk in children with atopic dermatitis
Topical therapy using corticosteroids or calcineurin inhibitors forms the main component of treating atopic dermatitis (AD) in children and adolescents. Although these medications are applied locally, their immunosuppressive properties can also manifest undesirably and theoretically increase the risk of skin and other malignancies. Isolated cases of melanoma and lymphoma have been reported, leading regulatory authorities in the United States and Europe to limit the duration of treatment with tacrolimus and pimecrolimus to 2 years and to…
Are Topical Calcineurin Inhibitors Really Such Demons?
Some medications indeed have significant side effects, while others suffer from a bad reputation…
Case Study of a Patient with NSCLC − with Voting
Presented by: MUDr. Leona Koubková,
Pneumology Clinic, 2nd Faculty of Medicine, Charles University...
Dupilumab – The First Biologic Umbrellaing Type 2 Inflammation Treatment: How Does It Work and Who Is It For?
A new drug is entering the market for the treatment of atopic dermatitis, asthma, and chronic…
Interaction of the 'Big Five' Helps Predict Depression
Experts refer to the 'Big Five' as a personality model that encompasses the following five…
Effect of 3 Different Doses of Trazodone on QT Interval Length
Patients diagnosed with depression often also suffer from cardiovascular diseases, including heart…
What Did the Patent for the Synthesis of Highly Purified Trazodone Bring?
Trazodone is a modern antidepressant that is used in the treatment of various types of depression,…
Long-term Clinical and Radiological Results of Implantation of Cementless Corail Stem
The Corail femoral stem with extensive hydroxyapatite coating for cementless implantation was…
Immunotherapy of Cancer Diseases
Immunotherapeutic strategies have been successfully utilized recently in the treatment of various malignancies....
Dynamics of Allergy Development in Children
The prevalence of allergic diseases in children in developed countries has been steadily increasing…