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Current Insights into the Antispasmodic and Analgesic Effects of Metamizole on the Gastrointestinal Tract
2. 11. 2020 Source: AnalgesiaBrazilian authors published a review of available information on the mechanism of action of metamizole, its impact on gastrointestinal tract motility, its effect on the gastric mucosa, and its antispasmodic effects.
Impact of Thyroid Dysfunction on the Cardiovascular System in Elderly Patients
The incidence of thyroid disease increases with age. In the Czech Republic, up to 5% of the population suffers from hypothyroidism, and the prevalence of hyperthyroidism is estimated at 0.2-1%. The…2. 11. 2020 Source: Thyroid Disorders
Rurioctocog alfa pegol in previously treated patients with severe hemophilia A: What findings did the long-term continuation study bring?
Rurioctocog alfa pegol (Adynovi) is a recombinant coagulation factor VIII modified by pegylation, which results in an approximately 1.5× prolonged biological half-life compared to standard half-life…2. 11. 2020 Source: Hemophilia
Position of aPCC in the Treatment of Hemophilia A Complicated by the Development of Inhibitors
Activated prothrombin complex concentrates (aPCC) are essential drugs that not only allow the control of bleeding in patients with congenital hemophilia A and inhibitors but also help to prevent such…2. 11. 2020 Source: Hemophilia
Anxiety Disorders and Autoimmune Thyroiditis – A Connection Rather Than Coincidence?
Anxiolytics commonly target the central nervous system. Newly published research by Ukrainian authors offers a different perspective – according to their findings, anxiety may be related to thyroid…29. 10. 2020 Source: Depression and Anxiety
Targeted Treatment and Quality of Life in Patients with Follicular Lymphoma
The GALLIUM clinical trial evaluated chemotherapy in combination with targeted treatment using rituximab or obinutuzumab in previously untreated patients with advanced follicular lymphoma (FL). A…27. 10. 2020 Source: Non-Hodgkin Lymphomas and CLL
Sport Therapy as Part of Hemophilia Management
A study by authors from the University of Wuppertal in Germany specifically examined the impact of a half-year programmed sport therapy on the subjective physical performance and quality of life of…27. 10. 2020 Source: Hemophilia with Movement
EHL preparations have the potential to change the quality of life for people with hemophilia
Within the therapeutic modalities for hemophilia, the current era offers a number of preparations. Newer extended half-life (EHL) replacement therapies can provide hemophiliacs with better protection…27. 10. 2020 Source: Hemophilia with Movement
Idiopathic Thrombocytopenic Purpura with SARS-CoV-2 Infection
To date, 45 cases of idiopathic (autoimmune) thrombocytopenic purpura (ITP) in individuals with confirmed SARS-CoV-2 infection have been published in the literature. In September 2020, a review…27. 10. 2020 Source: Immune Thrombocytopenia
Current Data on the Safety Profile of Baricitinib in the Treatment of Rheumatoid Arthritis
Baricitinib was approved for the treatment of rheumatoid arthritis (RA) in 2017, making it essential and relevant to monitor its safety profile in clinical practice. The analysis of data collected…26. 10. 2020 Source: Biological Treatment
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