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Current Results of Brigatinib in the Treatment of Lung Cancer

4. 6. 2021 Source: Non-Small Cell Lung Cancer

The results of the primary analysis showed a significant extension of PFS in patients with non-small cell lung cancer (NSCLC) treated with brigatinib compared to crizotinib. The recently published secondary analysis confirms these results.

Position of the Aclidinium-Bromide/Formoterol-Fumarate Combination in COPD Treatment According to Current Recommendations

Dual bronchodilator therapy, which combines long-acting muscarinic antagonists (LAMA) and long-acting β-agonists (LABA), has become an integral part of the treatment for chronic obstructive pulmonary…

3. 6. 2021 Source: Treatment of Asthma and COPD

Fixed combination tiotropium/olodaterol in regular clinical practice: What do patients say?

A non-interventional international study assessed the therapeutic benefits of the fixed combination of tiotropium/olodaterol in the treatment of chronic obstructive pulmonary disease (COPD) in…

28. 5. 2021 Source: COPD

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Thromboprophylaxis as a Common Part of Care for At-Risk Patients Requiring Hospitalization: Yes or No?

The proportion of patients requiring hospitalization who are at high risk of developing thromboembolic disease is relatively high. However, not all of these patients have this risk identified and…

28. 5. 2021 Source: Thromboprophylaxis

Thromboprophylaxis in Generalized Pancreatic Cancer

Pancreatic adenocarcinoma is one of the tumors with the highest risk of developing thromboembolic disease (TED). Although anticoagulant treatment reduces the risk of TED, its positive effect on the…

28. 5. 2021 Source: Thromboprophylaxis

Does Intense Monitoring After Colorectal Cancer Resection Bring Benefits?

Is it necessary to intensely monitor patients with colorectal cancer after curative resection? Not always, as shown by the results of the PRODIGE 13 study presented at the virtual ESMO 2020…

25. 5. 2021 Source: Colorectal Cancer

Metamizole in the Treatment of Acute Postoperative Pain

In many countries, metamizole is considered a first-choice non-opioid analgesic. The analysis presented below, published in the Cochrane Database of Systematic Reviews, examined the efficacy and…

25. 5. 2021 Source: Analgesia

Quality of Life of Hemophiliacs and Ways to Improve It

Determining the quality of life (QoL) also reflects the morbidity associated with the disease, in this case, hemophilia. In the study presented below, the authors focused on determining QoL in…

21. 5. 2021 Source: Hemophilia with Movement

Comparison of EHL Products in the Treatment of Hemophilia A –⁠ Pharmacoeconomic Analysis

In the work presented below, whose results were recently published, a model combining pharmacokinetic and pharmacodynamic data was developed. With its help, the authors tried to compare the bleeding…

21. 5. 2021 Source: Hemophilia with Movement

Comparison of Duloxetine, Gabapentin, and Pregabalin in the Treatment of Diabetic Neuropathic Pain

Painful diabetic neuropathy represents an unpleasant complication of diabetes, in which several groups of drugs are used in therapy. Among their representatives are duloxetine, gabapentin, and…

21. 5. 2021 Source: Neuropathic Pain

Pregabalin in the Treatment of Postherpetic Neuralgia Resistant to Gabapentin

Pregabalin appears to be an effective aid in patients with postherpetic neuralgia. This is evidenced by numerous clinical studies comparing the effects of pregabalin and gabapentin. It can be…

21. 5. 2021 Source: Neuropathic Pain

Case of Heparin Allergy and Preventive Administration of Fondaparinux in Pregnancy –⁠ Case Study

The presented case study discusses a complicated case of a 40-year-old woman with essential thrombocythemia (ET), a history of intrauterine fetal death, and recurrent pulmonary embolism (PE). The…

20. 5. 2021 Source: Management of Thrombosis in Women

Does Sacubitril/Valsartan Prevent Myocardial Remodeling in Heart Failure Patients with Type 2 Diabetes?

The PROVE-HF study demonstrated reverse myocardial remodeling in patients with chronic heart failure with reduced ejection fraction. About 30–50% of heart failure patients have type 2 diabetes…

20. 5. 2021 Source: Chronic Heart Failure and Lipidology

INFOGRAPHIC: Prevention and Management of Hypotension During Sacubitril/Valsartan Treatment

Despite the undeniable benefits of sacubitril/valsartan in terms of morbidity and mortality in patients with chronic heart failure, its administration can be complicated by side effects. The most…

20. 5. 2021 Source: Chronic Heart Failure and Lipidology

Thrombocytopenia Following mRNA Vaccination Against SARS-CoV-2

In connection with the administration of mRNA-based vaccines against the SARS-CoV-2 coronavirus, cases of secondary immune thrombocytopenia (ITP) have been described. A commentary published by a…

20. 5. 2021 Source: Immune Thrombocytopenia

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