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Biochemotherapy of Aggressive Rectal Carcinoma – A Case Study from the Czech Republic
Colorectal cancer arises from a complex interplay of environmental and lifestyle factors complemented by hereditary factors. Nowadays, it represents not only a health concern but also a socioeconomic problem. It is the second most common malignant tumor in both sexes; fortunately, its incidence and mortality have been decreasing in recent years. Due to expanding and more accurately targeted treatment options and good patient care management, it is also possible to better manage more aggressive and previously difficult-to-treat forms of the…
Incidence of Secondary Malignancies in CLL Patients on FCR Regimen in Central Europe
Chronic lymphocytic leukemia (CLL) represents the most common type of leukemia in Western countries…
Pathogenetic Mechanisms Underlying the Development and Progression of Interstitial Lung Diseases
Interstitial lung processes (ILP) represent an umbrella term for a wide range of nosological units…
Finding Balance Between Intracranial Efficacy and Adverse Effects of ALK Kinase Inhibition
More than 7 years – that is the current median survival of patients with non-small cell lung cancer…
What did the first data from the pilot lung cancer screening show?
Czech pulmonologists have released the first interim results of this year's pilot testing of heavy…
Presence of Risk Factors Associated with Colectomy in Patients with Ulcerative Colitis in Studies with Tofacitinib
One of the important goals of active ulcerative colitis therapy is the prevention of colectomy. A…
Prof. Petr Marusič: Is the Success of Therapy Changing with the Arrival of New Antiepileptics?
At the XXV. postgraduate course in epileptology, 'Jiří Dolanský Days', prof. MUDr. Petr Marusič,…
Severe Polytrauma in a Man with von Willebrand Disease − Case Report
The authors of a recently published case report present a case of multiple trauma (including brain…
Substitution Treatment of von Willebrand Disease with vWF and FVIII Concentrates
Recently published recommendations from Poland regarding the diagnosis and treatment of von…
ITP from the Patients' Perspective: How It Affects Their Lives and Which Needs They Find Unmet?
In recent years, new therapeutic options for immune thrombocytopenia (ITP) have been introduced,…