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Early and effective treatment of PBC significantly reduced the need for liver transplantation due to this disease

23. 6. 2022 Source: Primary Biliary Cholangitis

Current European and Czech guidelines include obeticholic acid (OCA) as the only registered option for 2nd line treatment of primary biliary cholangitis (PBC). In the Czech Republic, it is approved as a center-specific treatment and was granted permanent reimbursement from public health insurance in May 2022. The use of OCA in the treatment of PBC was also addressed in a symposium that was part of the professional program at this year's XLIX. May Hepatology Days in Olomouc.

muž dobrý pocit

Iron Deficiency and Administration of Ferric Carboxymaltose in Patients with Heart Failure

Iron deficiency is very common in patients with heart failure and is associated with exercise intolerance, reduced quality of life, increased mortality, and higher risk of hospitalization, regardless…
21. 6. 2022 Source: Iron Deficiency and Anemia
senior vnučka

Does empagliflozin improve the overall health of patients with heart failure with reduced LVEF?

A recently published secondary analysis of the EMPEROR-Reduced study is based mainly on the results of the KCCQ-23 questionnaire, which assesses the patient's health status from their perspective.…
21. 6. 2022 Source: Heart Failure
studie srdce 3

Comparison of Dabigatran and Vitamin K Antagonists in Patients with Atrial Fibrillation in Real-World Practice

The final 3-year results of the GLORIA-AF study conducted in real-world practice with patients newly diagnosed with atrial fibrillation show a lower incidence of major bleeding and lower overall…
21. 6. 2022 Source: Anticoagulant Treatment
Bolestivý kolenní kloub

Low-Molecular-Weight Heparins in Thromboprophylaxis After Major Orthopedic and Traumatological Procedures According to Current Recommendations

Patients after major orthopedic and traumatological procedures are at high risk of thromboembolic disease. This is especially true for people undergoing hip and knee replacement or patients with a proximal...
20. 6. 2022 Source: Thromboprophylaxis
karcinom kolorekta, CRC, Colorectal cancer

Successful Resection of a Rectosigmoid Tumor After Long-term Induction Biochemotherapy –⁠ A Case Report

Neoadjuvant treatment (chemoradiotherapy) for colorectal cancer is regularly used in advanced rectal tumors, with the goal of reducing the tumor size for the surgeon and ensuring the best possible…
20. 6. 2022 Source: Colorectal Cancer
atopická dermatitida detail kůže

Dupilumab Improves Skin and Systemic Symptoms of Atopic Dermatitis

A clinical study conducted in the USA and Canada demonstrated the efficacy of dupilumab in treating moderate to severe atopic dermatitis, improving both skin symptoms and suppressing systemic…
20. 6. 2022 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation
heal wounds

Current View on Prophylactic Negative Pressure Wound Therapy in Practice from Surgeons' Perspective

The journal Updates in Surgery recently published the results of a survey on prophylactic negative-pressure wound therapy (pNPWT) conducted among Swiss surgeons. The survey results show how often…
17. 6. 2022 Source: Wound Healing
klinicka studie

Comparison of the effects of fibrinogen concentrates and fresh frozen plasma in patients with acute traumatic coagulopathy

A quasi-experimental study compared the effectiveness of fibrinogen concentrates and fresh frozen plasma in patients with severe blunt trauma requiring the administration of erythrocyte replacements.
15. 6. 2022 Source: Life-threatening Bleeding
porod

Fibrinogen and Management of Peripartum Life-Threatening Hemorrhage

The most common cause of maternal death in the developed world continues to be peripartum life-threatening hemorrhage. It can result as a consequence of the consumption of coagulation factors,…
15. 6. 2022 Source: Life-threatening Bleeding
antihypertenzní léčba

Telmisartan, amlodipine, and chlorthalidone in a low-dose fixed triple combination –⁠ better control of target blood pressure values?

The secondary analysis of the TRIUMPH study, recently published in JAMA Cardiology, is likely the first published assessment of time spent in the target blood pressure (BP) range during…
15. 6. 2022 Source: Sartans in the Treatment of Hypertension
robot ovládaný joystickem

Joystick-operated robot intervening in stroke treatment remotely −⁠ fiction or promise of the future?

A team of experts from the Massachusetts Institute of Technology (MIT) has developed a telerobotic system that could allow doctors to treat stroke or brain aneurysm remotely in the future. Scientists…
15. 6. 2022 Source: medScope.pro
wound dressing care,

Current Indications for Negative Pressure Therapy in Wound Healing in Orthopedic and Traumatological Patients

Negative pressure wound therapy was introduced in North America in 1997. Since then, the method has gained great popularity and is used in the treatment of many acute and chronic wounds. Like any…
14. 6. 2022 Source: Wound Healing
aloe vera tablety

Which Dietary Recommendations Actually Work for Irritable Bowel Syndrome?

Food is both a trigger for symptoms and a treatment tool for individuals with irritable bowel syndrome (IBS). A 2021 review summarizes the results of the latest research on the effectiveness of…
13. 6. 2022 Source: Irritable Bowel Syndrome
renální insuficience

Efficacy and Safety of Enoxaparin in Hospitalized Patients with Severe Renal Insufficiency

A study evaluating the effect of thromboprophylaxis with enoxaparin at a dose of 20 mg/day in adult patients with renal failure compared the incidence of venous thromboembolism (VTE) with published…
13. 6. 2022 Source: Thromboprophylaxis
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