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Drops with Liposomal Ozonized Oil Reduce Ocular Microbial Burden Before Cataract Surgery

14. 11. 2023 Source: Treatment of Glaucoma

The periocular zone and conjunctiva are characterized by high microbial activity. Therefore, it is important to reduce this bacterial burden as part of preoperative prophylaxis before surgery to minimize the risk of infection. The aim of the study presented below, conducted in 20 Italian centers, was to evaluate the antimicrobial efficacy of a new ocular solution in patients undergoing cataract surgery.

Post hoc Analysis of the FRAME Study –⁠ Romosozumab in the Treatment of Osteoporosis in the European Population

An interesting finding from the FRAME study, which evaluated the treatment of postmenopausal women with osteoporosis using romosozumab, was the significant differences in fracture incidence among…

14. 11. 2023 Source: Osteoporosis – Trends in Sequential Therapy

Romosozumab vs. Teriparatide in Sequential Treatment of Osteoporosis in Women with a History of Fracture

The STRUCTURE study observed the effect of romosozumab and teriparatide on bone density in postmenopausal women with osteoporosis transitioning from bisphosphonate treatment over a 12-month period.

14. 11. 2023 Source: Osteoporosis – Trends in Sequential Therapy

How Important is the Time Factor in the Treatment of Heart Failure?

Current guidelines emphasize the importance of early diagnosis and immediate treatment for patients with heart failure (HF). These patients are most vulnerable immediately after the decompensation of…

13. 11. 2023 Source: Heart Failure

Transthyretin Amyloidosis in Patients with Carpal Tunnel Syndrome

Carpal tunnel syndrome is considered a warning sign for cardiac amyloidosis. Amyloid deposits are often found in the tenosynovial material removed during surgery. However, the prevalence of…

10. 11. 2023 Source: Amyloidosis

Inhibition of Mutated KRAS Protein as a New Option for Targeted Treatment of Non-Small Cell Lung Cancer

RAS proteins are molecular switches for several intracellular signaling pathways. Their dysfunction due to mutation leads to the development and progression of malignant diseases such as colon or…

9. 11. 2023 Source: Lung Cancer

MUDr. Tomáš Mašek: In the prevention of hemorrhoids, more use of venopharmaceuticals is needed

While in the past the diagnosis of hemorrhoids was inextricably linked to traditional surgical solutions, today -⁠ thanks to the expansion of the indication for venopharmaceuticals for this condition…

7. 11. 2023 Source: Venous Insufficiency

Balance and Rehabilitation –⁠ Firm on the Ground Even with Multiple Sclerosis

A large portion of patients with multiple sclerosis (MS) suffer from balance disorders. What are the options for non-pharmacological therapy for these issues according to the latest studies?

1. 11. 2023 Source: Multiple Sclerosis

Instead of NSAIDs, consider combining paracetamol with a weak opioid

Chronic non-cancer pain is a problem that primary care physicians encounter on a daily basis. In the following interview with general practitioner MUDr. Michaela Wichová, we discuss how to approach a…

1. 11. 2023 Source: Updates in Pain Treatment

Fixed combination tramadol/paracetamol as an effective and safe option for long-term pain treatment even in polymorbid patients

Combined analgesics were historically recommended exclusively for the treatment of acute or postoperative pain, mainly due to the risk of individual components which, although potentiated their…

1. 11. 2023 Source: Updates in Pain Treatment

Pharmacological Profile of Mavacamten and Key Studies of Its Use in HCM Treatment

A new addition to the treatment options for hypertrophic cardiomyopathy, approved for use in European Union countries in June 2023, is the selective reversible cardiac myosin inhibitor mavacamten.…

1. 11. 2023 Source: Hypertrophic Cardiomyopathy (HCM)

INFOGRAPHIC: Diagnosis and Monitoring of Patients with Hypertrophic Cardiomyopathy –⁠ Current Guidelines

What examinations should be conducted when suspecting hypertrophic cardiomyopathy, a hereditary disease caused by mutations in genes encoding cardiac muscle proteins? What is the subsequent procedure…

1. 11. 2023 Source: Hypertrophic Cardiomyopathy (HCM)

Neutropenia with Thrombocytopenia after Alemtuzumab? −⁠ Case Report

Early neutropenia with thrombocytopenia is not a common side effect of alemtuzumab. However, the patient in the following case report by Italian colleagues was affected. What was the outcome?

1. 11. 2023 Source: Multiple Sclerosis

Safety of aPCC in Real Practice –⁠ Results of the BAHAS Project

What are the experiences with activated prothrombin complex concentrate (aPCC) in controlling bleeding or preventing its recurrence in acquired hemophilia A? The BAHAS project from Spanish real…

31. 10. 2023 Source: Hemophilia

Streptococcus pneumoniae Serotype 3 Continues to Be the Most Frequent Cause of Invasive Pneumococcal Diseases in the Czech Republic

After 2 years influenced by the COVID-19 pandemic, the number of cases of invasive pneumococcal diseases (IPD) has returned to pre-2020 levels. Serotype 3 remains the most frequent cause of IPD for…

26. 10. 2023 Source: Regular Vaccination

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