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FOLFOXIRI and Panitumumab in mCRC Treatment – Improvement in Treatment Response and Metastasis Resectability
For patients with metastatic colorectal cancer (mCRC) who are able to undergo intensive treatment, the FOLFOX (5-fluorouracil/leucovorin, oxaliplatin) or FOLFIRI (5-fluorouracil/leucovorin, irinotecan) regimens combined with monoclonal antibodies represent the standard first-line treatment. The FOLFOXIRI regimen, which is another option, was developed to further enhance the efficacy of chemotherapy. The German oncologists' VOLFI study investigated the effectiveness of combining targeted therapy and triplet chemotherapy compared to chemotherapy…
Early Cytoreductive Treatment Delays Onset of Symptoms Associated with Metastatic Colorectal Carcinoma
Managing symptoms associated with advanced cancer has a significant impact on patients' quality of…
Itoprid helps diabetics with reduced gastrointestinal motility improve diabetes control
The prokinetic itoprid led not only to the alleviation of gastroparesis symptoms and an improvement…
Effect of Itopride on Esophageal Motility and Lower Esophageal Sphincter Function
Itopride is a prokinetic used in the therapy of functional non-ulcerous upper dyspeptic…
Can tofacitinib have a positive impact on the mental stress of patients with rheumatoid arthritis?
In the population of patients with rheumatoid arthritis (RA), there is a higher incidence of…
Educational Quiz (For Downtime)
The following quiz has been prepared for you as an activity for relaxation and unwinding from today's...
Significant Reduction in the Extent and Intensity of Psoriasis After Initiating Therapy with Skin Foam − Case Study
A case study from the Clinic of Skin and Venereal Diseases, Faculty of Medicine, Palacky…
Brodalumab – 5 Years of Data on Efficacy, Safety, and Quality of Life Improvement in Plaque Psoriasis
Chronic inflammatory diseases, including psoriasis, require therapeutic approaches that maintain…
Impact of Candesartan on Achieving Remission in Patients with Active IgA Nephropathy
IgA nephropathy is the most common glomerulonephritis worldwide and in the Czech Republic. The…
Impact of Lifestyle on the Benefit of Pharmacotherapy for Hypertension and Dyslipidemia
Antihypertensive and hypolipidemic therapy reduces the risk of cardiovascular (CV) diseases.…