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Primum non nocere applies not only in medicine: an ecological look at inhalers
According to estimates from the World Health Organization (WHO), around 65 million people worldwide suffer from mild to moderate forms of chronic obstructive pulmonary disease (COPD). The cornerstone of therapy is the inhalation administration of bronchodilator drugs. While there is no doubt that this therapy helps patients, what impact do the propellants in inhalation systems have on the global climate? And is there a sensible solution to this problem?
Effect of Beta-Blockers on Glucose Metabolism and Their Use in Diabetics with Hypoglycemic Episodes
Beta-blockers, through their mechanism of action, can lead to the deepening or direct initiation of…
Trazodone with Extended Release Improves Patient Compliance
Since 2015, the antidepressant trazodone is available in the Czech Republic in a controlled-release…
Ixekizumab administered for 5 years demonstrated high efficacy and a favorable safety profile in patients with moderate to severe psoriasis
Ixekizumab is a recombinant humanized monoclonal antibody against interleukin 17A, indicated for…
Incidence of Thromboembolic Disease During Military Operations – Results of a 10-Year Review
In contemporary armed conflicts, limb injuries account for more than half of all injuries. In…
Comparison of Three Thromboprophylactic Regimens in Patients Post Pancreatic Surgery
Post-pancreatectomy bleeding and thromboembolic disease are among the serious complications of…
Do Beta-Blockers Increase the Risk of Hypoglycemia in Patients with Diabetes and Atherosclerosis?
Given that a large portion of patients with diabetes have proven cardiovascular disease, several…
Impact of Body Mass Index on Survival and Treatment Outcomes of Metastatic Colorectal Cancer
A pooled analysis of 25 studies with patients in the first line of treatment for metastatic…
Testing RAS Gene Mutations in Patients with Colorectal Cancer
Correct identification of the RAS oncogene variant is crucial for deciding the treatment of…
Reimbursement vs. Indication: Are They Clashing in Alzheimer's Disease?
Data from clinical trials and recommended procedures do not always align with insurance…