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Combination of Candesartan with ACE Inhibitors in the Treatment of Hypertension and Heart Failure
Although the combination of ACE inhibitors and sartans is not recommended due to the higher incidence of complications, studies also indicate a positive effect of their concurrent administration. The potential use of dual blockade of the renin-angiotensin-aldosterone system (RAAS) is suggested in resistant hypertension, and results have also been described in the treatment of congestive heart failure. What do the recommendations say?
Development of Albuminuria During Treatment with ACE Inhibitors and Sartans
Individual molecules from the class of renin-angiotensin system inhibitors display various distinct…
Targeted DNA Sequencing Helps Find Targeted Therapy for Patients with NSCLC
Gene sequencing has become a key tool in deciding the treatment for patients with non-small cell…
Hypnotics in the Therapy of Insomnia (Not Only) in the Elderly
Problems with insomnia make up a significant part of the subjective complaints, especially of older…
Safety and efficacy of dabigatran and other NOACs compared with warfarin in patients with atrial fibrillation – results of a large long-term prospective study
Anticoagulant therapy is key in the prevention of strokes in patients with atrial fibrillation.…
Primum non nocere applies not only in medicine: an ecological look at inhalers
According to estimates from the World Health Organization (WHO), around 65 million people worldwide…
Effect of Beta-Blockers on Glucose Metabolism and Their Use in Diabetics with Hypoglycemic Episodes
Beta-blockers, through their mechanism of action, can lead to the deepening or direct initiation of…
Trazodone with Extended Release Improves Patient Compliance
Since 2015, the antidepressant trazodone is available in the Czech Republic in a controlled-release…
Ixekizumab administered for 5 years demonstrated high efficacy and a favorable safety profile in patients with moderate to severe psoriasis
Ixekizumab is a recombinant humanized monoclonal antibody against interleukin 17A, indicated for…
Incidence of Thromboembolic Disease During Military Operations – Results of a 10-Year Review
In contemporary armed conflicts, limb injuries account for more than half of all injuries. In…