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Prescription Restrictions on Antidiabetics Authorized for Prescription by General Practitioners -⁠ Status as of October 2020

15. 10. 2020 Source: Diabetes

Diabetes mellitus (DM) has become an increasing problem worldwide in recent years. Long-term complications of DM lead to increased morbidity and mortality in the diabetic population, and their prevention determines the main treatment goals of DM. The treatment and management of patients with type 2 diabetes (DM2) are provided by either a general practitioner's office (GP) or a diabetology clinic. According to available data, over 200,000 patients with DM2 are currently treated and managed in GP offices.

Kyselina obeticholová

Obeticholic Acid in the Treatment of Patients with Primary Biliary Cholangitis with Inadequate Response to Ursodeoxycholic Acid in Real Practice

An interim analysis of the OCARELIFE observational study presented at the European Association for the Study of the Liver (EASL) congress in August 2020 attempted to evaluate whether the safety and…
14. 10. 2020 Source: Primary Biliary Cholangitis

Nutritional Care as Part of Prehabilitation in Surgical Patients

Nutritional preparation of patients before surgery as part of prehabilitation can significantly affect the quality of recovery and physical condition of patients after surgery. This topic is…
14. 10. 2020 Source: Enteral Nutrition
Pomocné_ruce

Memantine and Donepezil –⁠ Unity is Strength

Memantine and donepezil are both used in the therapy of Alzheimer's disease (AD). However, how does the combination of these drugs fare in the treatment of moderate to severe AD?
12. 10. 2020 Source: Cognitive in the treatment of Alzheimer's disease
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Memantine Eases Daily Life for Patients and Caregivers

What is the efficacy and safety of memantine in patients with Alzheimer's disease in routine practice in the Czech Republic? And to what extent can it ease the burden on caregivers of these patients?
12. 10. 2020 Source: Cognitive in the treatment of Alzheimer's disease
kvalita života

What impact do the symptoms of primary biliary cholangitis have on the patient and their quality of life

Primary biliary cholangitis (PBC) is a serious chronic cholestatic autoimmune liver disease that predominantly affects middle-aged women and can lead to end-stage liver failure and the need for…
12. 10. 2020 Source: Primary Biliary Cholangitis
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Use of Targeted Therapy with Dupilumab in Patients with Allergic Diseases

Interleukins (IL) 4 and 13 play an important role in the pathogenesis of allergic diseases. Their blockade is therefore a suitable strategy for a number of these conditions. This is offered by the…
11. 10. 2020 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation
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Fixed Combination of Tramadol/Paracetamol in the Treatment of Chronic Lower Back Pain and Its Effect on Apathy in Chronically Algic Patients

Long-term chronic pain is associated with apathy, loss of motivation, and depression in patients. However, these comorbidities of chronic pain and their interconnections are still insufficiently…
9. 10. 2020 Source: Pharmacotherapy of Pain
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Can the Fixed Combination of Tramadol/Acetaminophen Significantly Reduce Back Pain Uncontrolled by NSAIDs?

One way to prevent drug-related complications in the treatment of lower back pain (LBP) while improving patients' functioning in daily activities is the prescription of the weak opioid agonist…
9. 10. 2020 Source: Pharmacotherapy of Pain
chemoterapie - pacient

Brentuximab Vedotin and Relapsing/Refractory NHL with High Expression of CD30

A recently published study by authors from South Korea focused on examining the efficacy of brentuximab vedotin in patients with non-Hodgkin lymphomas (NHL) that highly express CD30 (i.e., > 30%…
7. 10. 2020 Source: Hematologic Malignancies
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