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Liposomal Pegylated Irinotecan in the Treatment of Pancreatic Tumors
Combined treatment with liposomal pegylated irinotecan, 5-fluorouracil (5-FU), and leucovorin (LV) significantly improves overall survival in patients with metastatic ductal carcinoma of the pancreas. Analysis of the NAPOLI clinical trial revealed prognostic markers for long-term survival in patients treated this way.

New Treatment Option for Metastatic Pancreatic Cancer – Pegylated Liposomal Irinotecan
The 2019 review article is dedicated to the use of nanoliposomal irinotecan, its toxicity, and its…

What FVIII Levels Are Ideal for Preventing Bleeding in Hemophilia A?
Recent studies indicate that target trough levels of factor 1–3% during prophylactic treatment are insufficient...

Can Co-administration of Dabigatran with Antiretroviral Drugs Be Effective and Safe?
In 2019, the first results regarding the concurrent use of antiretroviral drugs and oral…

The Future and Prospects of Type 2 Diabetes Therapy: Can We Fully Cure It with Endoscopy or Genetics?
Diabetes mellitus (DM) cannot be cured, but it can be successfully treated... Will we rewrite this…

Thyroid Function During COVID-19 Illness and After Recovery
Acute infection with the SARS-CoV-2 coronavirus has varying impacts on different organ systems of…

Increase in Thyroid Cancer Incidence Due to the Coronavirus Pandemic?
According to available data, COVID-19 disease does not worsen the course of thyroid cancer.…

Sport and Physical Activity Benefit Hemophiliacs
Sport and physical activity are beneficial for individuals with hemophilia. This statement was…

Prenatal Phenotype of Children with Noonan Syndrome
Until recently, the various phenotypes of RASopathies were clinically diagnosed only after birth.…

Biological treatment of psoriatic arthritis in the 1st line – results of the SPIRIT-H2H study after 1 year of follow-up
The SPIRIT-H2H study compared the efficacy of ixekizumab and adalimumab, either as monotherapy or…