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Antiviral and Anti-inflammatory Effects of Alpha-1-Antitrypsin in the Treatment of COVID-19

14. 5. 2021 Source: Deficiency of Alpha-1-Antitrypsin

Human alpha-1-antitrypsin (AAT) is a circulating blood glycoprotein that has been used for decades in the treatment of patients with AAT deficiency, lung damage, and emphysema, helping to prevent acute lung injury. Recently, it has been found that AAT also mitigates the course of COVID-19 disease by hindering the entry of the SARS-CoV-2 coronavirus into host cells. This dual antiviral and anti-inflammatory action makes AAT an excellent candidate for COVID-19 treatment.

Laboratoř_měření_jaterní_hodnoty_ALP_test

To what extent can the actual level of ALP, ALT, or bilirubin differ from the measured value?

A physician who bases clinical decisions on laboratory-determined values of biological parameters…
14. 5. 2021 Source: Primary Biliary Cholangitis
Parkinsonova choroba_žena_asistentka_chodítko

Treatment of Motor Symptoms of Parkinson's Disease

Parkinson's disease (PD) is one of the few neurodegenerative disorders for which effective…
12. 5. 2021 Source: Parkinson's Disease
medicína žena břicho bolest žaludek stomie

Liposomal Pegylated Irinotecan in the Treatment of Pancreatic Tumors

Combined treatment with liposomal pegylated irinotecan, 5-fluorouracil (5-FU), and leucovorin (LV)…
11. 5. 2021 Source: Treatment of Gastrointestinal Carcinomas
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New Treatment Option for Metastatic Pancreatic Cancer – Pegylated Liposomal Irinotecan

The 2019 review article is dedicated to the use of nanoliposomal irinotecan, its toxicity, and its…
11. 5. 2021 Source: Treatment of Gastrointestinal Carcinomas
faktor VIII hemofilie krev zkumavka

What FVIII Levels Are Ideal for Preventing Bleeding in Hemophilia A?

Recent studies indicate that target trough levels of factor 1–3% during prophylactic treatment are insufficient...
10. 5. 2021 Source: Hemophilia
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Can Co-administration of Dabigatran with Antiretroviral Drugs Be Effective and Safe?

In 2019, the first results regarding the concurrent use of antiretroviral drugs and oral…
6. 5. 2021 Source: Anticoagulant Treatment
Lékař v chirurgickém oděvu drží endoskop v ruce. Pacient a sestra v pozadí.

The Future and Prospects of Type 2 Diabetes Therapy: Can We Fully Cure It with Endoscopy or Genetics?

Diabetes mellitus (DM) cannot be cured, but it can be successfully treated... Will we rewrite this…
6. 5. 2021 Source: Modern Treatment of Diabetes
Tým lékařů

Thyroid Function During COVID-19 Illness and After Recovery

Acute infection with the SARS-CoV-2 coronavirus has varying impacts on different organ systems of…
6. 5. 2021 Source: Thyroid Disorders
štítná žláza grafika

Increase in Thyroid Cancer Incidence Due to the Coronavirus Pandemic?

According to available data, COVID-19 disease does not worsen the course of thyroid cancer.…
6. 5. 2021 Source: Thyroid Disorders
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