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psriasis

Dual Inhibition of IL-17A/IL-17F Across the Spectrum of Axial Spondyloarthritis

1. 12. 2023 Source: Rheumatic Diseases

Many patients with axial spondyloarthritis (axSpA) still have a need to seek additional therapeutic options and new mechanisms of action for medicinal substances. Phase III studies BE MOBILE 1 and 2 therefore evaluated the effect of administering bimekizumab—a monoclonal antibody selectively inhibiting interleukins (IL) 17A and 17F—across the full spectrum of patients with axSpA.

PIDSID

Effectiveness and Safety of Initiating Treatment for Primary Immunodeficiency with Subcutaneously Administered Immunoglobulins –⁠ A Systematic Review of the Literature

The aim of the systematic review of the literature published last year was to evaluate the effectiveness and safety of initiating treatment with subcutaneously administered immunoglobulins (SCIG) in…
1. 12. 2023 Source: Primary and Secondary Immunodeficiencies
otaznik

10 Warning Signs of Primary and Secondary Immunodeficiencies

The Jeffrey Modell Foundation (JMF) proposed 10 warning signs of primary immunodeficiencies (PID). The study presented below examined whether they are applicable to secondary immunodeficiencies (SID)…
1. 12. 2023 Source: Primary and Secondary Immunodeficiencies
laboratorní diagnostika

Picking from the Red Book of the CHS: What's New in This Year's Recommendations for Diagnosis and Treatment of AML?

In recent years, there have been significant advances in the diagnosis and therapy of acute myeloid leukemia (AML). High-quality laboratory diagnostics (molecular genetics, cytogenetics, and flow…
29. 11. 2023 Source: Acute Myeloid Leukemia
CLL

Educational Brochure for Patients with CLL

Thanks to the expansion of modern therapies for chronic lymphocytic leukemia, many patients now have regimens based on venetoclax. Do you want to help them better understand the practical aspects and...
28. 11. 2023 Source: Chronic Lymphocytic Leukemia
mikroorganismy

Bacterial Biofilm as a Complication of Respiratory Disease Treatment

One of the unique characteristics of certain microorganisms is their ability to form organized communities enveloped in extracellular polymeric matrix and firmly attached to a solid surface or…
28. 11. 2023 Source: Cough Therapy
respiračního systém

Impact of erdostein on bacterial biofilm −⁠ and what it means for clinical practice?

One of the substances that could potentially influence the success of treatments for infections associated with biofilm formation in the future is erdostein. This medication is used in the treatment…
28. 11. 2023 Source: Cough Therapy
ECMO

Low Molecular Weight Heparin in an ECMO Patient −⁠ Case Study

Extracorporeal membrane oxygenation (ECMO) has an irreplaceable role in intensive care medicine. In the context of preventing complications caused by blood clot formation, unfractionated heparin is…
28. 11. 2023 Source: Thromboprophylaxis
enoxaparin

Use of Enoxaparin in Patients After Implantation of Left Ventricular Assist Device

Left ventricular assist devices (LVAD) are utilized in patients with end-stage heart failure (HF). Warfarin is typically employed for long-term anticoagulation, but there are no standardized…
28. 11. 2023 Source: Thromboprophylaxis
Žilní tromboembolická nemoc

Prophylaxis with Enoxaparin After Total Knee or Hip Replacement

Venous thromboembolic disease is a significant cause of complications in surgical patients during and after hospitalization. The authors of a recently published Portuguese observational study…
28. 11. 2023 Source: Thromboprophylaxis
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