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Use of Brodalumab in the Treatment of Severe Plaque Psoriasis − Case Report
The case report by MUDr. Jan Šternberský, Ph.D., from the Clinic of Skin and Venereal Diseases, UP Faculty of Medicine and University Hospital Olomouc, demonstrates the excellent effect of brodalumab in a patient with severe plaque psoriasis resistant to previous treatment modalities.
Hypotension during treatment with sacubitril/valsartan: practical tips for prevention and management
Despite the undeniable benefits of sacubitril/valsartan in terms of morbidity and mortality in…
Is it possible to predict survival time based on laboratory or radiological findings in patients with IPF?
High-resolution computed tomography (HRCT) imaging of the lungs is a fundamental examination in…
Gliflozins in the Treatment of Type 2 Diabetes According to Current Recommendations SVL
Gliflozins are a relatively new group of antidiabetics with a specific mechanism of action. In…
Combination of Arterial Hypertension and Increased Heart Rate as a Significant Cardiovascular Risk Factor
Heart rate is one of the basic vital signs that should be regularly measured. Sinus tachycardia can…
Is Six Months of Adjuvant Targeted Therapy Sufficient for Early Breast Cancer?
The inclusion of adjuvant targeted therapy with chemotherapy for early HER2-positive breast cancer…
Targeted Treatment of Metastatic Breast Cancer in the 2nd Line – Experiences from Practice
The recommended treatment for metastatic HER2-positive breast cancer in the 1st line involves dual…
Micronutrients in Parenteral Nutrition in Adult Patients – Current Issues and Consensus
Micronutrients are a key nutritional component, and this is also true for patients whose condition…
Residual Pulmonary Hypertension After Endarterectomy: How Common Is It?
Pulmonary endarterectomy is the only potentially curative option in the treatment of chronic…
Medium to Long-term Results of PFC Sigma Total Knee Arthroplasty
The PFC Sigma knee implant was introduced in 1997. It is the most commonly used system for total…