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Good Efficacy of Brigatinib After Failure of 2nd Generation ALK Inhibitors

15. 2. 2021 Source: Non-Small Cell Lung Cancer

Brigatinib is commonly used in the treatment of ALK-positive non-small cell lung cancer (NSCLC) in the 2nd line after progression on a 1st-generation ALK inhibitor, crizotinib. American scientists in a phase II study focused on the efficacy of brigatinib in the treatment of patients with advanced NSCLC who had progressed on 2nd-generation ALK inhibitors.

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Does olaparib improve overall survival in patients with recurrent ovarian cancer and BRCA mutation?

Olaparib, a poly(ADP-ribose) polymerase (PARP) enzyme inhibitor, in tablet form is indicated, among…
13. 2. 2021 Source: Ovarian and Breast Cancer
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Trazodone in the Treatment of Depressive Disorder –⁠ A Case Study

Presented by MUDr. Sylva Racková, Ph.D. Psychiatric Clinic, Plzeň
12. 2. 2021 Source: Depression and Anxiety
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Hydrotherapy in the Treatment of Non-Healing Wounds

For the treatment of wounds, it is crucial how they are managed during the cleaning and granulation…
10. 2. 2021 Source: Wound Healing
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International Recommendations for COVID-19 Vaccination in People with Bleeding Disorders

At the end of December 2020, international guidelines for COVID-19 vaccination in people with…
8. 2. 2021 Source: Hemophilia
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COVID-19: Specifics of Care for Individuals with Congenital Bleeding Disorders

The COVID-19 pandemic has significantly impacted nearly all medical fields. Alongside direct care…
8. 2. 2021 Source: Hemophilia
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Invasive Pulmonary Aspergillosis –⁠ A Common Accompanying Infection in Patients with Severe or Critical Course of COVID-19

Findings based on a literature review conducted and published in September 2020 show the occurrence…
8. 2. 2021 Source: Anti-Infectives
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Trifluridine/Tipiracil in the 3rd Line Treatment of mCRC −⁠ Case Study

The following case study describes the treatment of a patient with metastatic colorectal cancer…
3. 2. 2021 Source: Treatment of Gastrointestinal Carcinomas
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Atectura® and Enerzair®: new fixed dual and triple combination in the treatment of bronchial asthma

In mid-2020, the European Commission approved two new fixed combinations of drugs by Novartis for…
28. 1. 2021 Source: Asthma under control
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Recent Advances in Physiotherapy for Hemophiliacs

Physiotherapy specifically focuses on movement and the movement potential of the individual, with…
28. 1. 2021 Source: Hemophilia with Movement
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