News
Combined Treatment of Chronic Lymphocytic Leukemia in Frail Patients – Results from Real-World Clinical Practice
Treatment of older patients and those with chronic lymphocytic leukemia (CLL) who are not in good physical condition has advanced significantly in recent years. The addition of obinutuzumab to chlorambucil therapy has extended both progression-free survival and overall survival for patients. The authors of the presented study evaluated the efficacy and safety of obinutuzumab in real-world clinical practice.
Targeted Therapy for DLBCL Patients Who Cannot Undergo Bone Marrow Transplant
An international team of hemato-oncologists has been involved in testing polatuzumab vedotin in patients with diffuse large B-cell lymphoma (DLBCL) who have an unfavorable prognosis. In an article…
Comparison of Efficacy of Ixekizumab and Adalimumab in Patients with Psoriatic Arthritis and Moderate to Severe Psoriasis
Ixekizumab, a humanized monoclonal antibody against interleukin 17A (IL-17A), is approved in the Czech Republic for the treatment of active psoriatic arthritis (PsA) and moderate to severe plaque…
How to Improve Diabetic Adherence?
The dream of every doctor is a conscientious patient who follows the prescribed treatment and reports any potential problems in a timely manner. But where can such a patient be found?
Should patients with primary immunodeficiencies fear COVID-19 more than the general population?
The body fights the new SARS-CoV-2 virus, which causes COVID-19, in a similar way to other viral infections - by intensely engaging the immune system. But what if it's weakened?
Safety and Efficacy of Negative Pressure Therapy in Acute Infected Wounds
Negative Pressure Wound Therapy (NPWT) is a globally widespread wound care method. It involves creating a local negative pressure in the wound, with key benefits including moist wound healing in a closed...
Monotherapy with Bimatoprost in Patients with Glaucoma and Ocular Hypertension
Can monotherapy with bimatoprost be sufficiently effective in controlling intraocular pressure in non-responders to previous treatments? This is the question posed by British researchers in the…
Effectiveness of Arginine in Tooth Cleaning Proven (Not Only) by Quantitative Light-Induced Fluorescence
There is no doubt about the benefits of toothpaste in daily dental care. Today, there are numerous studies proving that brushing without toothpaste does not have the same effectiveness as brushing…
Concise and Practical Recommendations for Optimal Care of Dental Prostheses
Millions of people around the world use full or partial dental prostheses. However, there are no standardized global procedures with guidelines on how to care for dental prostheses. Dentists and…
Care for Dental Prostheses: What Did Clinical Study Results Reveal?
Dental prostheses are one of the most common solutions for missing teeth, especially in the elderly population. It is estimated that by 2050 up to 2 billion people will be aged 60 or older.…
New Era in Migraine Therapy
Migraine is the most common type of primary headache. It affects about 10% of the world population. Recurring migraine attacks significantly reduce quality of life. Therefore, research in…
Most Common Dermatoses Around the Stoma
The incidence of stomal complications ranges between 20 and 70%. One type of complication is dermatoses affecting the peristomal skin. These issues can occur in the early postoperative period, but…
Principle of Slowed Wound Healing Due to Stress Revealed
There is no doubt that psychological stress significantly slows down the process of healing wounds. The principle of how this phenomenon occurs, however, has remained unexplained. Swiss scientists focused...
Pertuzumab significantly extends the life of patients with metastatic breast cancer
The final results of the CLEOPATRA clinical trial show that patients with HER2-positive metastatic breast cancer achieve 8-year overall survival of 37% with the targeted treatment combination of…
Maintenance treatment with oral olaparib in women with BRCA1/2 mutation and relapsed ovarian cancer
In a phase III study published in the journal Lancet Oncology, data on the effectiveness of olaparib in patients with ovarian cancer and BRCA1/2 mutation were evaluated. The poly(ADP-ribose)…