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Idarucizumab reverses the anticoagulant effect of dabigatran even in patients with impaired renal function –⁠ clinical practice commentary

10. 2. 2020 Source: Anticoagulant Treatment

Along with the results of a subanalysis of the RE-VERSE AD study, which demonstrated the efficacy of idarucizumab in reversing the anticoagulant effect of dabigatran regardless of the level of renal function impairment, the October issue of the Journal of the American College of Cardiology also featured an editorial commentary by Californian cardiologists on its conclusions.

medicína_žena_těhotná_těhotenství_matka

Does The Use of Levothyroxine in Women with Thyroid Peroxidase Antibodies Affect The Risk of Miscarriage and Premature Birth?

Women with thyroid peroxidase antibodies have a higher risk of miscarriage and premature birth, even if they have normal thyroid function. The British study presented below aimed to clarify whether…
10. 2. 2020 Source: Thyroid Disorders
koleno ATTUNE® Knee System

Comparison of Clinical Outcomes of TKA Implantation: ATTUNE vs. SIGMA

The ATTUNE total knee arthroplasty (TKA) system was introduced to the market in 2013 as a successor to the popular SIGMA system. The new type of knee endoprosthesis is designed to provide better…
7. 2. 2020 Source: Large Joints
Pacienti s kašlem a bronchitidou

Clinical Benefit of Mucolytics in the Treatment of Upper Respiratory Tract Infections

A new review based on published controlled and observational studies as well as real-world practice experiences demonstrates the benefits of ambroxol, bromhexine, carbocisteine, erdosteine,…
6. 2. 2020 Source: Cough Therapy

Prevalence and Incidence of Age-Related Macular Degeneration in Europe –⁠ Current Overview and Trend Analysis

A comprehensive review article by authors from Bonn, Germany, published late last year in the British Journal of Ophthalmology, provides current data and estimates of the incidence and prevalence of…
6. 2. 2020 Source: Glaucoma
vysledky_interpretace

Changes in Intestinal Microflora Correlate with Disease Activity in Patients with Lupus Erythematosus

The role of intestinal microflora in the pathogenesis of autoimmune diseases, including lupus erythematosus, has been discussed for a long time. An American study discovered a specific bacterium…
4. 2. 2020 Source: Arthritis
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Risk Factors and Therapy of Chronic Leg Ulcers Lasting More Than 6 Months

The therapy of chronic leg ulcers in diabetics continues to be a significant challenge for attending physicians and surgeons. Authors of a recently published study have addressed the risk factors, clinical...
3. 2. 2020 Source: Wound Healing
LDL cholesterol

LDL cholesterol: a new risk factor for the onset of venous thromboembolic disease?

Not only do atherosclerotic plaques in the arteries and the risk of heart attack decrease along with LDL cholesterol levels. Results from a large molecular genetic study suggest that lowering its…
3. 2. 2020 Source: Cardiovascular Risks

Polatuzumab Vedotin in Combination Treatment of Patients with R/R DLBCL

Polatuzumab Vedotin is a conjugate of a cytostatic agent and an antibody against CD79b, a component of the B-lymphocyte receptor typically expressed by diffuse large B-cell lymphoma (DLBCL) cells. In…
3. 2. 2020 Source: Non-Hodgkin Lymphomas and CLL
zhodnocení výsledků vyšetření u lékaře 2356x1571

End of Unnecessary Biopsies? Prostate Health Index (PHI) in Detecting Aggressive Carcinoma

The Prostate Health Index (PHI) combines the results of three blood-derived parameters: total PSA (tPSA), free PSA (fPSA), and [-2]proPSA (p2PSA) into a single numerical score: PHI = (p2PSA / fPSA ×…
2. 2. 2020 Source: Prostate Health Index
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