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Treatment of Immune Thrombocytopenia: Choice of TPO Mimetics in Clinical Practice

20. 2. 2020 Source: Immune Thrombocytopenia

Real-world data show that the administration of thrombopoietin receptor agonists in immune thrombocytopenia leads to a high percentage of treatment responses, and in some patients, it is possible to achieve a stable response without the need for further treatment after discontinuation.

Current ASH Guidelines for Management of ITP 2019 −⁠ Recommendations for Newly Diagnosed ITP in Adults

The American Society of Hematology (ASH) published current guidelines for immune thrombocytopenia (ITP) at the end of 2019, where a panel of experts attempted to define evidence-based recommendations…
20. 2. 2020 Source: Immune Thrombocytopenia
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Metformin and Cardiovascular Disease in Patients with Type 2 Diabetes and Chronic Kidney Disease

Diabetes mellitus is a serious chronic disease that, due to its ever-increasing prevalence, poses a significant problem for society in developed countries. The main cause of morbidity and mortality…
19. 2. 2020 Source: Modern Treatment of Diabetes
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Are SGLT2 Inhibitors Only Suitable for the Treatment of Diabetes?

SGLT2 inhibitors, or gliflozins, are effective antidiabetic drugs that have shown nephroprotective and cardioprotective effects in diabetics, repeatedly demonstrated in clinical trials. At the…
19. 2. 2020 Source: Modern Treatment of Diabetes
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How to Manage Thromboprophylaxis in Obese and Extremely Obese Patients?

Doctors often address the question of how to dose thromboprophylaxis in overweight individuals. The goal is to ensure effective protection against thrombotic complications in stressful situations,…
18. 2. 2020 Source: Thromboprophylaxis

Positive Effect of Pregabalin Not Only on Neuropathic Pain in Patients with Spinal Cord Injury

Spinal cord injury is often accompanied by painful conditions. A study published in the prestigious journal Neurology demonstrated that administering pregabalin to these patients can bring more than…
18. 2. 2020 Source: Neuropathic Pain
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Pregabalin in the Hands of a General Practitioner

A recent Cochrane systematic review by authors from Oxford University examined the effect of pregabalin in the treatment of postherpetic neuralgia and diabetic neuropathy –⁠ conditions that general…
18. 2. 2020 Source: Neuropathic Pain
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Can We Lump All Gabapentinoids Together?

General practitioners often encounter peripheral neuropathic pain in their practice. One of the primary modalities for treating both painful diabetic neuropathy and postherpetic neuralgia is…
18. 2. 2020 Source: Neuropathic Pain
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Valproate for Acute Mania: Is Practice Really Evidence-Based and Recommended?

Authors from the University of Western Ontario conducted an audit in an acute psychiatric intake unit to determine whether the prescription of valproate there corresponded to evidence-based…
18. 2. 2020 Source: Bipolar Disorder
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Low-Molecular-Weight Heparin as Adjuvant Therapy in Small-Cell Lung Cancer −⁠ Results of the RASTEN Study

Several studies and meta-analyses in the past have pointed to a possible positive effect of low-molecular-weight heparins (LMWH) in the treatment of cancer. The RASTEN study therefore focused on the…
18. 2. 2020 Source: Thromboprophylaxis
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