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Safety of Riociguat in the Treatment of Thromboembolic Pulmonary Hypertension in Common Practice

16. 5. 2021 Source: Pulmonary hypertension (CTEPH, PAH)

In March 2021, the final safety results of riociguat in the treatment of thromboembolic pulmonary arterial hypertension in real-world practice were published from the international EXPERT registry, which also included Czech patients. The safety profile of the therapy was consistent with the findings of previous clinical studies.

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Alpha-1-Antitrypsin Deficiency and Its Association with Atopy in Asthmatics

Literature mentions the coincidence of asthma and alpha-1-antitrypsin deficiency, which is caused…
14. 5. 2021 Source: Deficiency of Alpha-1-Antitrypsin
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Antiviral and Anti-inflammatory Effects of Alpha-1-Antitrypsin in the Treatment of COVID-19

Human alpha-1-antitrypsin (AAT) is a circulating blood glycoprotein that has been used for decades…
14. 5. 2021 Source: Deficiency of Alpha-1-Antitrypsin
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To what extent can the actual level of ALP, ALT, or bilirubin differ from the measured value?

A physician who bases clinical decisions on laboratory-determined values of biological parameters…
14. 5. 2021 Source: Primary Biliary Cholangitis
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Treatment of Motor Symptoms of Parkinson's Disease

Parkinson's disease (PD) is one of the few neurodegenerative disorders for which effective…
12. 5. 2021 Source: Parkinson's Disease
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Liposomal Pegylated Irinotecan in the Treatment of Pancreatic Tumors

Combined treatment with liposomal pegylated irinotecan, 5-fluorouracil (5-FU), and leucovorin (LV)…
11. 5. 2021 Source: Treatment of Gastrointestinal Carcinomas
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New Treatment Option for Metastatic Pancreatic Cancer –⁠ Pegylated Liposomal Irinotecan

The 2019 review article is dedicated to the use of nanoliposomal irinotecan, its toxicity, and its…
11. 5. 2021 Source: Treatment of Gastrointestinal Carcinomas
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What FVIII Levels Are Ideal for Preventing Bleeding in Hemophilia A?

Recent studies indicate that target trough levels of factor 1–3% during prophylactic treatment are insufficient...
10. 5. 2021 Source: Hemophilia
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Can Co-administration of Dabigatran with Antiretroviral Drugs Be Effective and Safe?

In 2019, the first results regarding the concurrent use of antiretroviral drugs and oral…
6. 5. 2021 Source: Anticoagulant Treatment
Lékař v chirurgickém oděvu drží endoskop v ruce. Pacient a sestra v pozadí.

The Future and Prospects of Type 2 Diabetes Therapy: Can We Fully Cure It with Endoscopy or Genetics?

Diabetes mellitus (DM) cannot be cured, but it can be successfully treated... Will we rewrite this…
6. 5. 2021 Source: Modern Treatment of Diabetes
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