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Why does the heart enlarge? Myosin mutation and hypertrophic cardiomyopathy may be the culprits
7. 9. 2023 Source: Hypertrophic Cardiomyopathy (HCM)The genetic basis of hypertrophic cardiomyopathy was discovered only about a quarter-century ago. Since then, researchers have gathered a wealth of knowledge about the effects of causal mutations. Today, new drugs are available that directly target the molecular basis of the disease. The following text explains how mutations in heart muscle proteins are linked to myocardial hypertrophy.
Current View on Gestational Diabetes Mellitus in Theory and Practice
We dedicated one of the episodes of our podcast meditalks+ to the issue of gestational diabetes mellitus (GDM), focusing on aspects of care related to general practitioners. In a conversation with …7. 9. 2023 Source: Modern Treatment of Diabetes
ESMO Recommendations for the Treatment of Low-Risk Myelodysplastic Syndrome
The priority in the treatment of low-risk myelodysplastic syndrome (MDS) is managing cytopenia, primarily anemia, as well as neutropenia and thrombocytopenia. The following summary of recommendations…6. 9. 2023 Source: medScope.pro
Effect of Luspatercept Treatment in Patients with MDS/MPN-RS-T
The presented post hoc analysis of the MEDALIST study demonstrates the effect and good tolerance of luspatercept in the rare disease from the myelodysplasia group − MDS/MPN-RS-T.6. 9. 2023 Source: medScope.pro
Association between Hypothyroidism, Depression, and Anxiety Disorder – Results of Meta-Analyses
The prevalence of autoimmune thyroiditis in the USA ranges between 4 and 13%. Subclinical hypothyroidism affects 3–8.5% of the general population. Patients with this condition are at risk not only…6. 9. 2023 Source: Thyroid Disorders
A Look at Tongue and Its Care from the Perspective of Western and Traditional Chinese Medicine
The tongue is a valuable diagnostic tool used in both Traditional Chinese Medicine (TCM) and Western medicine. While the approaches to tongue care between these two medical systems differ…6. 9. 2023 Source: Dental Care
Management of Adverse Effects During Maintenance Treatment of AML Patients
The randomized phase III study QUAZAR AML-001 evaluated the maintenance treatment of acute myeloid leukemia (AML) in patients after first remission. The following text summarizes the findings…4. 9. 2023 Source: Acute Myeloid Leukemia
SCOPE 2021 – State of Osteoporosis and Its Treatment in European Countries
The SCOPE 2021 project (The Scorecard for Osteoporosis in Europe) by the International Osteoporosis Foundation (IOF) gathered and tabulated data from 29 European countries on the burden of…4. 9. 2023 Source: Osteoporosis – Trends in Sequential Therapy
Risk of Subsequent Fractures in Postmenopausal Women After Initial Fracture
Osteoporosis is associated with an increased risk of fractures. The prospective analysis presented below examined the risk of subsequent fractures in postmenopausal women after an initial fracture…4. 9. 2023 Source: Osteoporosis – Trends in Sequential Therapy
Laboratory Safety of Dupilumab Treatment in Children with Atopic Dermatitis Aged 6 Months to 6 Years
Previous clinical studies in children aged 6–12 years with moderate-to-severe atopic dermatitis have demonstrated laboratory safety during dupilumab treatment. The randomized study presented below…
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