Medical News
Balance and Rehabilitation – Firm on the Ground Even with Multiple Sclerosis
A large portion of patients with multiple sclerosis (MS) suffer from balance disorders. What are the options for non-pharmacological therapy for these issues according to the latest studies?
Instead of NSAIDs, consider combining paracetamol with a weak opioid
Chronic non-cancer pain is a problem that primary care physicians encounter on a daily basis. In the following interview with general practitioner MUDr. Michaela Wichová, we discuss how to approach a…
Fixed combination tramadol/paracetamol as an effective and safe option for long-term pain treatment even in polymorbid patients
Combined analgesics were historically recommended exclusively for the treatment of acute or postoperative pain, mainly due to the risk of individual components which, although potentiated their…
Pharmacological Profile of Mavacamten and Key Studies of Its Use in HCM Treatment
A new addition to the treatment options for hypertrophic cardiomyopathy, approved for use in European Union countries in June 2023, is the selective reversible cardiac myosin inhibitor mavacamten.…
INFOGRAPHIC: Diagnosis and Monitoring of Patients with Hypertrophic Cardiomyopathy – Current Guidelines
What examinations should be conducted when suspecting hypertrophic cardiomyopathy, a hereditary disease caused by mutations in genes encoding cardiac muscle proteins? What is the subsequent procedure…
Neutropenia with Thrombocytopenia after Alemtuzumab? − Case Report
Early neutropenia with thrombocytopenia is not a common side effect of alemtuzumab. However, the patient in the following case report by Italian colleagues was affected. What was the outcome?
Safety of aPCC in Real Practice – Results of the BAHAS Project
What are the experiences with activated prothrombin complex concentrate (aPCC) in controlling bleeding or preventing its recurrence in acquired hemophilia A? The BAHAS project from Spanish real…
Streptococcus pneumoniae Serotype 3 Continues to Be the Most Frequent Cause of Invasive Pneumococcal Diseases in the Czech Republic
After 2 years influenced by the COVID-19 pandemic, the number of cases of invasive pneumococcal diseases (IPD) has returned to pre-2020 levels. Serotype 3 remains the most frequent cause of IPD for…
Multimodal Treatment of Prostate Cancer in a Patient with Exceptionally Long Overall Survival − Case Report
A recently published case study by Romanian authors presents a rare instance of long-term survival (15 years) in a patient with locoregional prostate cancer that later metastasized. The case…
Benefit of Short-term Androgen-deprivation Therapy Added to Radiotherapy of Localized Prostate Cancer for Long-term Survival
Androgen-deprivation therapy is associated with several adverse effects that also affect quality of life or increase the risks of serious age-related health problems. An extensive study focused on…
How Does the Long-Term Effect of Beta Blocker Use Affect Clinical Outcomes in Patients After Myocardial Infarction?
In patients after myocardial infarction (MI), beta blockers (BB) still hold an important place in secondary prevention according to recommended procedures. However, the question could be their…
Thanks to Buccolam, the reality of suppressing convulsive seizures in children and adolescents approaches parents' ideal management
What crosses the mind of a parent when they notice their epileptic child or adolescent is having a convulsive seizure? They want it to be over quickly and safely. What constitutes the integral part…
Treatment of Low-Risk MDS According to NCCN Recommendations Version 1.2023
The latest recommendations from the American National Comprehensive Cancer Network (NCCN) for the diagnosis and treatment of myelodysplastic syndrome (MDS) include several updates incorporated into…
ERS 2023: Erdostein and its Metabolite Met-1 Modulate Innate Immunity and Oxidative Stress in SARS-CoV-2 Infection
As part of the September congress of the European Respiratory Society (ERS 2023), the issue of COVID-19 was also addressed. Among the late-breaking messages was an e-poster by experts from the…
Benefit of Empagliflozin in Patients with Chronic Kidney Disease – Results of the EMPA-KIDNEY Study
The sodium-glucose cotransporter 2 inhibitor (SGLT2i) empagliflozin is currently used to treat type 2 diabetes mellitus (T2DM) and chronic heart failure regardless of ejection fraction value. Its…