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Polatuzumab Vedotin in the Treatment of NHL -⁠ News from the 25th EHA Congress

29. 9. 2020 Source: Non-Hodgkin Lymphomas and CLL

Polatuzumab vedotin (Polivy) is approved in the EU for the treatment of patients with relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL), for whom hematopoietic stem cell transplantation (HSCT) is not suitable. We provide an overview of the latest news regarding the role of this modern medicine in the therapy of non-Hodgkin's lymphomas (NHL), presented at the 25th Congress of the European Hematology Association (EHA), held virtually due to the pandemic situation.

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How to Secure Diabetics with Atrial Fibrillation During PCI?

Optimal management of patients with atrial fibrillation undergoing percutaneous coronary intervention (PCI) continues to be the subject of studies. A sub-analysis of the RE-DUAL study focused on this…
29. 9. 2020 Source: Anticoagulant Treatment
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Safety of Dabigatran in the Secondary Prevention of Venous Thromboembolism in Children

The direct thrombin inhibitor dabigatran is used by adult patients, among others, in the secondary prevention of venous thromboembolism (VTE). Its safety in the pediatric population was the focus of…
29. 9. 2020 Source: Anticoagulant Treatment
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Is It Better to Switch or Cycle in the Treatment of Rheumatoid Arthritis?

The ideal strategy for treating rheumatoid arthritis is still the subject of research. We therefore present the results of a recent study comparing the impact of various therapeutic options when…
24. 9. 2020 Source: Arthritis
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Remarkable Findings from the Subanalysis of the Efficacy and Safety of Teriflunomide in the Chinese Population with MS in Relation to Global Results

Teriflunomide, from the group of disease-modifying drugs (DMDs), intended for the treatment of patients with multiple sclerosis (MS), inhibits the proliferation of lymphocytes. As a result, fewer…
24. 9. 2020 Source: Multiple Sclerosis
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Satisfaction of Patients Treated with Platinum Derivatives with Antiemetic Therapy

The fixed oral combination of netupitant with palonosetron (NEPA) is used for the prevention of nausea and vomiting induced by cytotoxic chemotherapy. A prospective German study evaluated the benefit…
23. 9. 2020 Source: Antiemetic Therapy
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Simple antiemetic prophylaxis for breast cancer patients treated with AC chemotherapy

The combination of an anthracycline cytostatic agent with cyclophosphamide (AC) is among the highly effective chemotherapy regimens for breast cancer. Individually, these cytostatic agents carry a…
23. 9. 2020 Source: Antiemetic Therapy
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Observational Study of Pegylated rVIII Administration in Real Clinical Practice

A recently published article by American hematologists provided valuable information about the treatment with pegylated recombinant factor VIII (rVIII) in real clinical practice. This is the most…
21. 9. 2020 Source: Hemophilia

Cost-effectiveness in Bleeding Control for Acquired Hemophilia A

A pharmacoeconomic analysis showed favorable cost-effectiveness of activated prothrombin complex concentrate in the indication of bleeding control in patients with acquired hemophilia A.
18. 9. 2020 Source: Hemophilia
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Comparison of Efficacy of Bisoprolol and Metoprolol ZOK in Patients with Mild to Moderate Hypertension –⁠ Results of the CREATIVE Study

Suppression of increased activity in the sympathoadrenal system is currently one of the main goals of antihypertensive therapy. Beta-blockers play an important role in regulating the sympathetic…
17. 9. 2020 Source: Cardiovascular Continuum
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