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Good Efficacy of Brigatinib After Failure of 2nd Generation ALK Inhibitors

15. 2. 2021 Source: Non-Small Cell Lung Cancer

Brigatinib is commonly used in the treatment of ALK-positive non-small cell lung cancer (NSCLC) in the 2nd line after progression on a 1st-generation ALK inhibitor, crizotinib. American scientists in a phase II study focused on the efficacy of brigatinib in the treatment of patients with advanced NSCLC who had progressed on 2nd-generation ALK inhibitors.

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Does olaparib improve overall survival in patients with recurrent ovarian cancer and BRCA mutation?

Olaparib, a poly(ADP-ribose) polymerase (PARP) enzyme inhibitor, in tablet form is indicated, among other things, for the maintenance treatment of adult patients with platinum-sensitive recurrent…
13. 2. 2021 Source: Ovarian and Breast Cancer
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Hydrotherapy in the Treatment of Non-Healing Wounds

For the treatment of wounds, it is crucial how they are managed during the cleaning and granulation phases. For most non-healing wounds, so-called Hydrotherapy (treatment with hydroresponsive…
10. 2. 2021 Source: Wound Healing
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International Recommendations for COVID-19 Vaccination in People with Bleeding Disorders

At the end of December 2020, international guidelines for COVID-19 vaccination in people with bleeding disorders were published on the World Federation of Hemophilia (WFH) website. We present a basic…
8. 2. 2021 Source: Hemophilia
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COVID-19: Specifics of Care for Individuals with Congenital Bleeding Disorders

The COVID-19 pandemic has significantly impacted nearly all medical fields. Alongside direct care focused on seriously ill patients, the pandemic also affects the care of chronic patients, including…
8. 2. 2021 Source: Hemophilia
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Invasive Pulmonary Aspergillosis –⁠ A Common Accompanying Infection in Patients with Severe or Critical Course of COVID-19

Findings based on a literature review conducted and published in September 2020 show the occurrence of invasive pulmonary aspergillosis (IPA) in 19.6–33.3% of patients with a severe or critical…
8. 2. 2021 Source: Anti-Infectives
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Atectura® and Enerzair®: new fixed dual and triple combination in the treatment of bronchial asthma

In mid-2020, the European Commission approved two new fixed combinations of drugs by Novartis for patients with uncontrolled asthma –⁠ the dual combination Atectura® (LABA+ICS) and the triple…
28. 1. 2021 Source: Asthma under control
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Recent Advances in Physiotherapy for Hemophiliacs

Physiotherapy specifically focuses on movement and the movement potential of the individual, with the purpose of restoring or maintaining maximum mobility and functional abilities throughout life.…
28. 1. 2021 Source: Hemophilia with Movement
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Turoctocog Alfa Pegol with Extended Half-Life in the Treatment of Severe Hemophilia A

GlycoPEGylated recombinant factor VIII (rFVIII) with an extended half-life, turoctocog alfa pegol, has demonstrated prophylactic efficacy in patients with severe hemophilia A aged over 12. This…
28. 1. 2021 Source: Hemophilia with Movement
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Candesartan Could Ameliorate the Cytokine Storm in COVID-19 Infection

Scientists from Bethesda, USA, experimentally found the upregulation of the same genes during COVID-19 infection as with the action of glutamate (simulating aging and Alzheimer's disease) and the…
27. 1. 2021 Source: Sartans in the Treatment of Hypertension
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