Medical News
Somapacitan administered once weekly in the treatment of children with growth hormone deficiency – current understanding
Somapacitan is a long-acting derivative of recombinant human growth hormone approved for the treatment of children and adults with growth hormone (GH) deficiency. Dr. Reiko Horikawa from Japan's National Center for Child Health and Development in Tokyo, during the 24th Pediatric Endocrinology Days held in Brno in January 2024, showed that it is a promising therapeutic option for pediatric patients from 3 years of age, thanks to its efficacy, safety, and potential to improve therapy adherence. However, careful long-term monitoring of the safety…
Evaluation of Joint Condition in Daily Practice in the Era of New Hemophilia Treatment
With the development of new treatment options for hemophilia, there has also been progress in methods for monitoring hemophilic arthropathy and identifying it in its early stages. In addition to…
Collagen Turnover as a Biomarker of Hemophilia Treatment Efficacy
Over the past decades, hemophilia treatment has made significant progress—from factor therapy to prophylactic regimens and non-factor products, and even to gene therapy. Its development has greatly…
Alarming Data on Prevalence and Insufficient Treatment of Hypertension in Working Age − Another Underestimated 'Civilization Epidemic'?
The National Cardiology Information System (NKIS), developed by the Czech Society of Cardiology in collaboration with the Institute of Health Information and Statistics (ÚZIS), has provided the first…
With Prof. Pavel Žák about Current Trends and Future Perspectives in Bone Marrow Transplantation and the Role of Carmustine in this Context
Hematopoietic stem cell transplantation has an indispensable place in the treatment of hemato-oncological diseases. We discuss current trends in this area, the significance and benefits of…
Current Trends in Proton RT of Head and Neck Tumors: Aiming to Preserve T Lymphocytes, Without Them, Treatment is Ineffective
Tumors of the head and neck are often diagnosed at an advanced stage. With the availability of modern treatments, such as immunotherapy or radiotherapy modalities, prognosis and chances for long-term…
What Effect Can Be Expected from Limosilactobacillus reuteri in Mucositis and Peri-Implantitis?
A Spanish clinical study monitored the effect of administering probiotics as an adjunct therapy to non-surgical mechanical treatment of peri-implantitis. What did the study show regarding the effect…
X-ray in Dentistry: Who Can Indicate and Who Can Perform?
X-ray is an integral and important part of dental diagnostics. However, since it is also a source of ionizing radiation, its use is subject to legislative regulations that govern it.
Long-term survival of a 50-year-old man with metastatic pancreatic cancer on a combination of nal-IRI + 5-FU/LV in 2nd line treatment − case study
A recently published case study from the Czech Republic describes a patient with progression of pancreatic cancer following surgical treatment and adjuvant chemotherapy, who achieved a one-year…
Human Papillomavirus in Adults – HPV Does Not Choose Gender
A significant part of the population is exposed to human papillomaviruses (HPV) throughout their lives. In recent years, there has been a global effort to increase vaccination coverage not only among...
Safety of Metamizole in Adult Patients – Meta-analysis of 79 Studies
Metamizole is a non-opioid analgesic with antipyretic and spasmolytic effects that has been used for over 100 years. It is approved for the treatment of children and adults in various dosage forms.…
Metamizole – wide possibilities of an analgesic with a unique mechanism of action and different routes of administration
Metamizole is a non-addictive pyrazolone analgesic with antipyretic effects, which differs from other non-opioid analgesics by its spasmolytic action. It is indicated in monotherapy and in…
How to vaccinate children against pneumococcus?
Pneumococcus is a dreaded pathogen causing serious diseases in pediatric patients. However, it can be effectively prevented with commonly available vaccines. Let's look at the updated recommendation…
The Potential of Vinpocetine in the Treatment of Cardiovascular Diseases
Vinpocetine is a nootropic indicated for the symptomatic treatment of cerebral ischemic hypoperfusion, vascular dementia, and reducing the psychological and neurological consequences of cerebral…