Medical News
Can tofacitinib have a positive impact on the mental stress of patients with rheumatoid arthritis?
In the population of patients with rheumatoid arthritis (RA), there is a higher incidence of depression and anxiety compared to the healthy population. These psychiatric comorbidities can lead to a reduced quality of life and a poorer response to treatment. The aim of the post-hoc analysis presented below was to monitor the effect of tofacitinib on improving anxiety and depression in patients with RA.
Educational Quiz (For Downtime)
The following quiz has been prepared for you as an activity for relaxation and unwinding from today's hectic days. In an easy manner, it will refresh your knowledge about immune cells and may even offer...
Significant Reduction in the Extent and Intensity of Psoriasis After Initiating Therapy with Skin Foam − Case Study
A case study from the Clinic of Skin and Venereal Diseases, Faculty of Medicine, Palacky University, and University Hospital Olomouc, describes the treatment course of psoriasis in a young patient…
Brodalumab – 5 Years of Data on Efficacy, Safety, and Quality of Life Improvement in Plaque Psoriasis
Chronic inflammatory diseases, including psoriasis, require therapeutic approaches that maintain efficacy and tolerability even during long-term treatment. One such modern modality is brodalumab, a…
Impact of Candesartan on Achieving Remission in Patients with Active IgA Nephropathy
IgA nephropathy is the most common glomerulonephritis worldwide and in the Czech Republic. The effect of candesartan (an angiotensin receptor blocker) on the remission of active IgA nephropathy in…
Impact of Lifestyle on the Benefit of Pharmacotherapy for Hypertension and Dyslipidemia
Antihypertensive and hypolipidemic therapy reduces the risk of cardiovascular (CV) diseases. Observational studies have shown that factors of a healthy lifestyle also have this influence. But is the…
Incontinence as a Consequence of Surgical Procedure on the Prostate
Despite the advent of new surgical methods, urinary incontinence after prostate procedures remains a clinically significant iatrogenic complication. For patients, it represents a significant stress…
6 Years Follow-Up of Patients with Breast Cancer in the APHINITY Study
The primary analysis of results from the APHINITY clinical trial supported the combined anti-HER2 treatment with trastuzumab and pertuzumab in combination with chemotherapy in patients with early…
Idiopathic Pulmonary Fibrosis from the Perspective of an Outpatient Pulmonologist
Idiopathic pulmonary fibrosis represents a rare disease of lung tissue with an as-yet-unexplained etiology. In the framework of differential diagnosis, it is necessary to consider the disease, as…
Thinking About Idiopathic Pulmonary Fibrosis?
Idiopathic pulmonary fibrosis (IPF) is one of the most prognostically severe and difficult-to-treat lung diseases. It affects about 5 million people worldwide, with an estimated incidence in the…
American Heart Association: Side Effects of Statins Overview and Context
The American Heart Association (AHA) report provides an updated summary of knowledge on the safety of statin use. Despite warnings appearing in professional literature and general media, it assures…
Third Generation Targeted Therapy for ROS1-Positive NSCLC
The potent third-generation tyrosine kinase inhibitor, lorlatinib, has shown activity in preclinical studies against nearly all known mutations in the ALK and ROS1 genes that lead to resistance to…
Key Role of HRCT in Diagnosing Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis is often an unjustly overlooked disease. The truth is that it is a rare disease, but the prognosis for patients is very poor. To improve quality of life and chances of…
The Choice of Incontinence Aids Matters − But How Not to Get Lost Among Them?
Despite significant advances in medicine, a large number of patients still struggle with incontinence, which limits their comfort and reduces their quality of life. If treatment options have been…
Prevalence of Diabetics Among Patients with COVID-19 and the Impact of DM on the Course of Infection
Italian authors published the results of a meta-analysis of studies at the end of March, assessing the prevalence of diabetes among individuals infected with SARS-CoV2 and the impact of diabetes on…