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Idiopathic Pulmonary Fibrosis: Can This Disease Be Named More Precisely?

9. 9. 2021 Source: Progressive Interstitial Pulmonary Processes

Much about idiopathic pulmonary fibrosis (IPF) is still unknown. Some experts would like to reclassify this disease. What classification options are available? What would a focus on the "progressive fibrotic phenotype" in research mean? And what would a change in classification mean for patients?

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Brigatinib in the Therapy of ALK-Positive NSCLC in Patients Refractory to Crizotinib Therapy –⁠ Results of the Final Analysis of Clinical Studies

Previously published results of clinical studies have shown that in patients refractory to crizotinib therapy, the administration of brigatinib led to a high rate of therapeutic response (systemic…
9. 9. 2021 Source: Non-Small Cell Lung Cancer
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Brigatinib in the Therapy of ALK-Positive NSCLC –⁠ First Results of the J-ALTA Study

Brigatinib is an anaplastic lymphoma kinase (ALK) inhibitor with broad and potent activity against ALK gene mutations causing resistance to ALK inhibitor therapy (ALKi). In patients refractory to…
9. 9. 2021 Source: Non-Small Cell Lung Cancer
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Ivabradine and/or Sacubitril/Valsartan in the Treatment of Heart Failure with Reduced Ejection Fraction

Ivabradine and sacubitril/valsartan are used in the second line of therapy for heart failure with reduced ejection fraction (HFrEF). The aim of the study presented below was to evaluate the…
7. 9. 2021 Source: Chronic Heart Failure and Lipidology
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Variability of COPD Symptoms During the Day and Impact on Patients' Morning Routine –⁠ Survey Results

Chronic obstructive pulmonary disease (COPD) is viewed, unlike bronchial asthma, as a condition with a more chronic course and less variability of symptoms throughout the day. The study presented…
7. 9. 2021 Source: COPD
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Atectura® and Enerzair® from May 1, 2021 with Health Insurance Coverage

The fixed combination of indacaterol acetate (LABA) and mometasone furoate (ICS) Atectura® and the fixed triple combination, which in addition to these two substances also includes glycopyrronium…
2. 9. 2021 Source: Asthma under control
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New Strategies in the Treatment of Schizophrenia

Schizophrenia was primarily associated with dopamine dysfunction. Previous and current treatments have mainly targeted the mesolimbic dopamine pathway in the CNS and D2 receptors. However, the cited…
30. 8. 2021 Source: Schizophrenia and Antipsychotics
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Is it safe to start dabigatran in the first days after ischemic stroke?

For patients after cardioembolic ischemic stroke (iCMP), starting anticoagulant therapy is crucial, but it is not strictly defined how many days after iCMP it is ideal to begin. The article provides…
27. 8. 2021 Source: Anticoagulant Treatment
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Is the combination of tiotropium/olodaterol proven more effective in reducing the risk of clinically significant worsening of COPD compared to monotherapy?

Given the heterogeneity of chronic obstructive pulmonary disease (COPD), the use of a composite parameter that includes lung function, the occurrence of exacerbations, and quality of life offers a…
26. 8. 2021 Source: COPD
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Impact of Chronic Urticaria on Patients' Quality of Life and Society

An international team of dermatologists has mapped out the impact of chronic urticaria on various aspects of patients' lives and the economic burden this long-term disease, without available causal…
25. 8. 2021 Source: Allergic Reactions
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